{"active_ingredient":["Active Ingredient Lidocaine 4%","Active Ingredient Menthol 1%","Active Ingredient Camphor 3%","Active Ingredient Dimethicone 3%"],"ask_doctor":["Stop Use and Ask a Doctor If Condition worsens Excessive skin irritation develops Symptoms persist for more than 7 days, or symptoms clear up and occur again within 3 days"],"do_not_use":["Do Not Use On damaged or irritated skin With a bandage or heating pad If you are allergic to any ingredients in this product Other than as directed"],"dosage_and_administration":["Directions Ad ults and Children 12 years of Age and Older: Clean and dry the affected area Apply product directly to your skin, up to 4 times daily"],"effective_time":"20231214","id":"0c7d382a-b977-6159-e063-6294a90a886f","inactive_ingredient":["Inactive I ngredients Aloe Barbadensis Leaf Juice, Arnica Montana Flower, Boswellia Serrata Extract, Carbomer, Ethylhexylglycerin, FD&C Blue #1, Methylsulfonylmethane, Phenoxyethanol, Polysorbate 20, SD-Alcohol 40B, Sorbitol, Triethanolamine, Water. Questions or Comments? (877) 985-8377"],"indications_and_usage":["Uses : For the temporary relief of joint pain and muscle pain associated with: Arthritis Backache Discomfort Cramps Neckache Soreness Sprains Strains"],"keep_out_of_reach_of_children":["Keep Out of Reach of Children If ingested, seek medical help or contact a Poison Control Center immediately"],"openfda":{},"package_label_principal_display_panel":["Principal Display Panel neptune ice"],"pregnancy_or_breast_feeding":["If You Are Pregnant or Breast Feeding Ask a health professional before use"],"purpose":["Purpose Topical Anesthetic","Purpose Topical Analgesic","Purpose Topical Analgesic","Purpose Skin Conditioner"],"questions":["Questions or Comments? (877) 985-8377"],"set_id":"7759b4c9-ff17-2c69-e053-2a91aa0a2559","spl_product_data_elements":["Neptune Ice Lidocaine, Menthol, Camphor, and Dimethicone Gel ALOE VERA LEAF POLYSORBATE 20 FD&C BLUE NO. 1 ETHYLHEXYLGLYCERIN ARNICA MONTANA FLOWER PHENOXYETHANOL CARBOXYPOLYMETHYLENE BOSWELLIA SERRATA RESIN OIL WATER DIMETHYL SULFONE ALCOHOL TROLAMINE SORBITOL CAMPHOR (NATURAL) CAMPHOR (NATURAL) DIMETHICONE DIMETHICONE LIDOCAINE LIDOCAINE MENTHOL MENTHOL"],"spl_unclassified_section":["Methemoglobinemia Cases of methemoglobinemia have been reported in association with local anesthetic use. Although all patients are at risk for methemoglobinemia, patients with glucose-6-phosphate dehydrogenase deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants under 6 months of age, and concurrent exposure to oxidizing agents or their metabolites are more susceptible to developing clinical manifestations of the condition. If local anesthetics must be used in these patients, close monitoring for symptoms and signs of methemoglobinemia is recommended. Signs and symptoms of methemoglobinemia may occur immediately or may be delayed some hours after exposure and are characterized by a cyanotic skin discoloration and abnormal coloration of the blood. Methemoglobin levels may continue to rise; therefore, immediate treatment is required to avert more serious central nervous system and cardiovascular adverse effects, including seizures, coma, arrhythmias, and death. Discontinue lidocaine-containing products and any other oxidizing agents. Depending on the severity of the symptoms, patients may respond to supportive care, i.e., oxygen therapy, hydration. More severe symptoms may require treatment with methylene blue, exchange transfusion, or hyperbaric oxygen","DRUG FACTS","Other Information Store in a cool, dry place with lid tightly closed"],"version":"10","warnings":["Warnings For External Use Only Flammable Keep away from excessive heat or open flame Do Not Use On damaged or irritated skin With a bandage or heating pad If you are allergic to any ingredients in this product Other than as directed When Using This Product Avoid contact with the eyes Stop Use and Ask a Doctor If Condition worsens Excessive skin irritation develops Symptoms persist for more than 7 days, or symptoms clear up and occur again within 3 days If You Are Pregnant or Breast Feeding Ask a health professional before use Keep Out of Reach of Children If ingested, seek medical help or contact a Poison Control Center immediately"],"when_using":["When Using This Product Avoid contact with the eyes"]}