{"active_ingredient":["Active ingredient Benzoyl Peroxide 5%"],"dosage_and_administration":["Directions Cleanse skin thoroughly before applying Nighttime Control. Cover entire affected area with a thin layer 1 to 3 times daily. Because excessive drying of the skin may occur, start with 1 application every day, or every other day, gradually increasing to 2 or 3 times a day if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. Follow directions on sunscreen labeling. If sensitivity develops, discontinue use of both products and consult a doctor. If going outside apply a sunscreen after using this product."],"effective_time":"20231215","id":"0c86a86e-1d0e-8fa8-e063-6294a90a5963","inactive_ingredient":["Inactive ingredients Water, hexyldecanol, methyl propanediol, cetearyl alcohol, glyceryl stearate, PEG-100 stearate, cetereth-20, cetearyl glucoside, dimethicone, carbomer, tocopheryl acetate, allantoin, sodium hydroxide, caprylyl glycol, hexylene glycol, methylisothiazolinone"],"indications_and_usage":["Uses for the treatment of acne"],"keep_out_of_reach_of_children":["Keep Out of Reach of Children In case of accidental ingestion, get medical help or contact a Poison Control Center Immediately."],"openfda":{"application_number":["M006"],"brand_name":["Nighttime Control"],"generic_name":["BENZOYL PEROXIDE"],"is_original_packager":[true],"manufacturer_name":["Circadia by Dr Pugliese, Inc."],"package_ndc":["76458-333-02"],"product_ndc":["76458-333"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["106309"],"spl_id":["0c86a86e-1d0e-8fa8-e063-6294a90a5963"],"spl_set_id":["fb4cc832-4cfd-4e29-a78e-ab848681a224"],"substance_name":["BENZOYL PEROXIDE"],"unii":["W9WZN9A0GM"]},"package_label_principal_display_panel":["Package/Label Principal Display Panel Nighttime Control Benzoyl Peroxide Lotion Advanced Professional Skincare 2 fl oz (59 ml) Circadia by Dr. Pugliese, Inc. 8371 Route 183 Bethel, PA 19507 Circadia.com Label"],"purpose":["Purpose Acne Treatment"],"questions":["Questions? Call toll-free (800) 630-4710"],"set_id":"fb4cc832-4cfd-4e29-a78e-ab848681a224","spl_product_data_elements":["Nighttime Control Benzoyl Peroxide CARBOMER INTERPOLYMER TYPE A (ALLYL SUCROSE CROSSLINKED) BENZOYL PEROXIDE BENZOYL PEROXIDE WATER HEXYLDECANOL METHYLPROPANEDIOL CETOSTEARYL ALCOHOL GLYCERYL 1-STEARATE PEG-100 STEARATE CETEARYL GLUCOSIDE DIMETHICONE .ALPHA.-TOCOPHEROL ACETATE ALLANTOIN CAPRYLYL GLYCOL HEXYLENE GLYCOL METHYLISOTHIAZOLINONE SODIUM HYDROXIDE POLYOXYL 20 CETOSTEARYL ETHER"],"spl_unclassified_section":["Other Information Keep tightly closed Keep away from heat"],"stop_use":["Stop use and ask a doctor if irritation becomes severe. ask a doctor before using. If pregnant or breastfeeding,"],"version":"5","warnings":["Warnings For external use only Do not use if you When using this product have very sensitive skin are sensitive to benzoyl peroxide avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration at the same time as other topical acne medications, increased dryness or irritation is more likely to occur. If this occurs, only one medication should be used unless directed by a doctor."]}