{"active_ingredient":["Active ingredient Zinc Oxide 12%"],"ask_doctor":["Stop use and ask a doctor if • rash occurs."],"do_not_use":["Do not use • on broken skin."],"dosage_and_administration":["Directions Adults and children 6 months and older: • Apply generously 15 minutes before sun exposure • Reapply: • at least every 2 hours • after 40 minutes of swimming or sweating • immediately after towel drying • Children under 6 months of age: Ask a doctor • Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF value of 15 or higher and other sun protection measures including: • Limit time in the sun, especially from 10 a.m. to 2 p.m. • Wear long-sleeve shirts, pants, hats, and sunglasses."],"effective_time":"20240308","id":"1329e56d-1e75-4bcc-e063-6394a90ae0c3","inactive_ingredient":["Inactive Ingredients Water, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Jojoba Esters, Propanediol, Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate, Tridecyl Salicylate, Nylon-12, Niacinamide, Methylpropanediol, Silica, Glycerin, Sodium Chloride, Coco-Caprylate, Polyglyceryl-2 Dipolyhydroxystearate, Caprylyl Glycol, Bisabolol, Allantoin, Oryza Sativa (Rice) Bran Extract, Lecithin, Stearalkonium Hectorite, Polyglyceryl-3 Diisostearate, Polyglyceryl-3 Polyricinoleate, Phenylpropanol, Helianthus Annuus (Sun‑ower) Extract, Tocopherol, Rosmarinus Of­cinalis (Rosemary) Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide."],"indications_and_usage":["Uses • helps prevent sunburn. • if used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun."],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, call a poison control center or get medical help right away."],"openfda":{"application_number":["M020"],"brand_name":["Avene Multi-Defense Fluid"],"generic_name":["ZINC OXIDE"],"is_original_packager":[true],"manufacturer_name":["Pierre Fabre USA Inc."],"package_ndc":["64760-778-01"],"product_ndc":["64760-778"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"spl_id":["1329e56d-1e75-4bcc-e063-6394a90ae0c3"],"spl_set_id":["1329e56d-1e74-4bcc-e063-6394a90ae0c3"],"substance_name":["ZINC OXIDE"],"unii":["SOI2LOH54Z"]},"package_label_principal_display_panel":["Box 338075 Box 338075"],"purpose":["Purpose Sunscreen"],"questions":["Questions? 1-866-41-AVENE (28363)"],"set_id":"1329e56d-1e74-4bcc-e063-6394a90ae0c3","spl_product_data_elements":["Avene Multi-Defense Fluid Zinc oxide MEDIUM-CHAIN TRIGLYCERIDES PROPANEDIOL CAPRYLYL GLYCOL TOCOPHEROL TETRASODIUM GLUTAMATE DIACETATE ZINC OXIDE ZINC OXIDE TRIDECYL SALICYLATE NYLON-12 NIACINAMIDE METHYLPROPANEDIOL SILICON DIOXIDE ALLANTOIN STEARALKONIUM HECTORITE WATER JOJOBA OIL, RANDOMIZED POLYGLYCERYL-4 DIISOSTEARATE/POLYHYDROXYSTEARATE/SEBACATE GLYCERIN SODIUM CHLORIDE POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE LEVOMENOL RICE BRAN SOYBEAN LECITHIN PHENYLPROPANOL ROSEMARY POLYGLYCERYL-3 DIISOSTEARATE SODIUM HYDROXIDE ALKYL (C12-15) BENZOATE COCO-CAPRYLATE POLYGLYCERYL-3 PENTARICINOLEATE HELIANTHUS ANNUUS FLOWERING TOP"],"spl_unclassified_section":["Drug Facts","Other Information • Protect this product in this container from excessive heat and direct sun."],"version":"1","warnings":["Warnings For external use only."]}