{"active_ingredient":["Active ingredients (in each effervescent tablet) Anydrous citric acid 1000 mg Aspirin 325 mg (NSAID)* Sodium bicarbonate (heat-treated) 1916 mg *Nonsteroidal anti-inflammatory drug"],"adverse_reactions":["Questions or comments? 1-888-423-0139"],"ask_doctor":["Ask a doctor before use if ■ stomach bleeding warning applies to you ■ you have a history of stomach problems, such as heartburn ■ you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ■ you are taking a diuretic ■ you have asthma ■ you have a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are Ask a doctor or pharmacist before use if you are ■ presently taking a prescription drug. Antacids may interact with certain prescription drugs. ■ taking a prescription drug for anticoagulation (thinning the blood), diabetes, gout or arthritis"],"do_not_use":["Do not use Do not use ■ if you are allergic to aspirin or any other pain reliever/fever reducer ■ if you have ever had an allergic reaction to this product or any of its ingredients."],"dosage_and_administration":["Directions ■ do not exceed recommended dosage ■ to avoid serious injury, completely dissolve tablets in 4oz. of water before taking ■ adults and children 12 years and over (up to 60 years of age): 2 tablets every 4 hours - do not exceed 8 tablets in 24 hours ■ 60 years and over: 2 tablets every 4 hours - do not exceed 4 tablets in 24 hours ■ Childern under 12 years: consult a doctor Take this product any time - morning, noon or night - when you need relief from heartburn, acid indigestion, sour stomach with headache or body aches and pains. Place two (2) tablets in 4 oz of water. Dissolve tablets completely. You do not have to drink any of the residue that may be on the bottom of the glass. The medicines are in the water."],"effective_time":"20241113","id":"26d10f9a-a58e-eddf-e063-6394a90a166b","inactive_ingredient":["Inactive ingredients ■ none"],"indications_and_usage":["Uses Uses for the temporary relief of ■ heartburn, acid indigestion and sour stomach when accompanied by headache or body aches and pains ■ upset stomach with headache from overindulgence in food or drink ■ headache, body aches, and pain alone"],"keep_out_of_reach_of_children":["Keep out of reach of children. Keep out of reach of children."],"openfda":{"application_number":["M013"],"brand_name":["TopCare Effervescent Antacid and Pain Relief"],"generic_name":["ASPIRIN, CITRIC ACID, SODIUM BICARBONATE"],"is_original_packager":[true],"manufacturer_name":["Topco Associates LLC"],"nui":["N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832","N0000175833","N0000175835","N0000175980","N0000008556","N0000175089"],"package_ndc":["36800-421-68"],"pharm_class_cs":["Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]","Calculi Dissolution Agent [EPC]","Anti-coagulant [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]","Acidifying Activity [MoA]","Calcium Chelating Activity [MoA]"],"pharm_class_pe":["Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]","Decreased Coagulation Factor Activity [PE]"],"product_ndc":["36800-421"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1536675"],"spl_id":["26d10f9a-a58e-eddf-e063-6394a90a166b"],"spl_set_id":["639f9d57-f26a-708a-e053-2a91aa0a6962"],"substance_name":["ASPIRIN","SODIUM BICARBONATE","ANHYDROUS CITRIC ACID"],"unii":["R16CO5Y76E","8MDF5V39QO","XF417D3PSL"],"upc":["0036800128873"]},"other_safety_information":["Other information ■ each tablet contains: sodium 524 mg ■ store at room temperature (59º-86ºF)"],"overdosage":["In case of overdose In case of overdose, get medical help or contact a Poison Control Center right away."],"package_label_principal_display_panel":["PACKAGE LABEL. PRINCIIPAL DISPLAY PANEL Top Care Pain 36"],"pregnancy_or_breast_feeding":["If pregnant or breastfeeding If pregnant or breastfeeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":["Purpose Anhydrous citric acid 1000 mg...........................................Antacid Aspirin 325 mg (NSAID)* ....................................................Pain reliever Sodium bicarbonate (heat-treated) 1916 mg......................Antacid *Nonsteroidal anti-inflammatory drug"],"set_id":"639f9d57-f26a-708a-e053-2a91aa0a6962","spl_product_data_elements":["TopCare Effervescent Antacid and Pain Relief Aspirin, Citric Acid, Sodium Bicarbonate ASPIRIN ASPIRIN SODIUM BICARBONATE BICARBONATE ION ANHYDROUS CITRIC ACID ANHYDROUS CITRIC ACID L421"],"stop_use":["Stop use and ask a doctor if Stop use and ask a doctor if ■ you experience any of the following signs of stomach bleeding ■ feel faint ■ vomit blood ■ have bloody or black stools ■ have stomach pain that does not get better ■ an allergic reaction occurs. Seek medical help right away. ■ pain lasts for more than 10 days or gets worse ■ new symptoms occur ■ redness or swelling is present ■ ringing in the ears or a loss of hearing occurs"],"version":"6","warnings":["Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy Alert: Aspirin may cause a severe allergic reaction which may include: ■ hives ■ facial swelling ■ asthma (wheezing) ■ shock Stomach Bleeding Warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you ■ are age 60 or older ■ have had stomach ulcers or bleeding problems ■ take a blood thinning (anticoagulant) or steroid drug ■ take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ■ have 3 or more alcoholic drinks every day while using this product ■ take more or for a longer time than directed."],"when_using":["When using this product When using this product do not take more than 8 tablets (adults) or 4 tablets (60 years and over) in a 24-hour period or use the maximum dosage for more than 2 weeks, except under the advise and supervision of a physician."]}