{"active_ingredient":["Active Ingredient Sodium fluoride 0.243% (0.16% w/v fluoride ion)"],"dosage_and_administration":["Directions Adults and children 2 years of age and and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist. Do not swallow. To minimize swallowing use a pea-sized amount in children under 6. Supervise children's brushing until good habits are established. Children under 2 years: ask a dentist."],"effective_time":"20250101","id":"2aabeb4e-9700-aa53-e063-6294a90a98f6","inactive_ingredient":["Inactive Ingredients GLYCERIN, HYDRATED SILICA, SODIUM HEXAMETAPHOSPHATE, WATER, PEG-6, FLAVOR, TRISODIUM PHOSPHATE, SODIUM LAURYL SULFATE, CARRAGEENAN, COCAMIDOPROPYL BETAINE, SODIUM SACCHARIN, SUCRALOSE, XANTHAN GUM, TITANIUM DIOXIDE, MICA, CHARCOAL POWDER, SODIUM CHLORIDE, CITRUS LIMON(LEMON) FRUIT EXTRACT, XYLITOL, CANNABIS SATINA SEED OIL, PROPOLIS EXTRACT, BIFIDA FERMENT EXTRACT FILTRATE"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children. Keep out of reach of children under 6 years of age. Do not swallow. If you accidentally swallow more than used for brushing, seek professional assistance or contact a poison control center right away. If an allergic reaction develops, discontinue use immediately."],"openfda":{"application_number":["M021"],"brand_name":["PERIOE Microbiome Whitening Cool Mint"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Tai Guk Pharm. Co., Ltd."],"package_ndc":["43136-810-01"],"product_ndc":["43136-810"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["2aabeb4e-9700-aa53-e063-6294a90a98f6"],"spl_set_id":["de97dbea-dc8c-ebfa-e053-2995a90a2270"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"],"upc":["0803954304947"]},"package_label_principal_display_panel":["Principal Display Panel - 116 g Tube Carton PERIOE MICROBIOME TOOTHPASTE THE POWER OF PREBIOTICS helps support good bacteria to maintain healthy balance WHITENING REMOVES STAINS EFFECTIVELY with special whitening agent COOL MINT 116 g net wt. 4.1. oz LABEL_TUBE_PERIOE MICROBIOME WHITENING TOOTHPASTE 116g LABEL_CASE_PERIOE MICROBIOME WHITENING TOOTHPASTE 116g"],"purpose":["Purpose Anticavity toopaste"],"questions":["Questions? 1-800-FOR-AVON"],"set_id":"de97dbea-dc8c-ebfa-e053-2995a90a2270","spl_product_data_elements":["PERIOE Microbiome Whitening Cool Mint Sodium Fluoride POLYETHYLENE GLYCOL 300 PROPOLIS WAX SODIUM POLYMETAPHOSPHATE CARRAGEENAN GLYCERIN WATER COCAMIDOPROPYL BETAINE SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS SODIUM LAURYL SULFATE XYLITOL SACCHARIN SODIUM SACCHARIN SUCRALOSE TITANIUM DIOXIDE CITRUS LIMON FRUIT OIL SODIUM CHLORIDE HYDRATED SILICA XANTHAN GUM MICA ACTIVATED CHARCOAL CANNABIS SATIVA SEED OIL SODIUM FLUORIDE FLUORIDE ION Cool"],"spl_unclassified_section":["Drug Facts Drug Facts"],"version":"2","warnings":["Warnings Warnings Keep out of reach of children. Keep out of reach of children under 6 years of age. Do not swallow. If you accidentally swallow more than used for brushing, seek professional assistance or contact a poison control center right away. If an allergic reaction develops, discontinue use immediately."]}