{"active_ingredient":["ACTIVE INGREDIENT (IN EACH CAPLET) Acetaminophen USP, 650 mg"],"ask_doctor":["Ask a doctor before use if you have liver disease."],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin."],"do_not_use":["Do not use • with any other drugs containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. • if you are allergic to acetaminophen or any of the inactive ingredients in this product."],"dosage_and_administration":["DIRECTIONS • do not take more than directed (see overdose warning) adults • take 2 caplets every 8 hours with water • swallow whole; do not crush, chew, split or dissolve • do not take more than 6 caplets in 24 hours • do not use for more than 10 days unless directed by a doctor under 18 years of age • ask a doctor"],"dosage_and_administration_table":["<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\"><tbody><tr styleCode=\"Botrule\"><td styleCode=\"Lrule Rrule\" valign=\"middle\"><content styleCode=\"bold\"> adults</content></td><td styleCode=\"Rrule\" valign=\"middle\"> &#x2022; take 2 caplets every 8 hours with water   &#x2022; swallow whole; do not crush, chew, split or dissolve   &#x2022; do not take more than 6 caplets in 24 hours   &#x2022; do not use for more than 10 days unless directed by a doctor </td></tr><tr><td styleCode=\"Lrule Rrule\" valign=\"middle\"><content styleCode=\"bold\"> under 18 years   of age </content></td><td styleCode=\"Rrule\" valign=\"middle\"> &#x2022; ask a doctor</td></tr></tbody></table>"],"effective_time":"20260701","id":"2b89d8dc-aa00-5564-20a9-269c26d7d14f","inactive_ingredient":["INACTIVE INGREDIENTS hydroxyethyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, pregelatinized starch, sodium starch glycolate, stearic acid"],"indications_and_usage":["USES • temporarily relieves minor aches and pains due to: • minor pain of arthritis • muscular aches • backache • premenstrual and menstrual cramps • the common cold • headache • toothache • temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children Overdose warning: In case of overdose, get medical help or contact a poison control center right away.(1-800 222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms"],"openfda":{"application_number":["ANDA211544"],"brand_name":["8 HR Arthritis Pain"],"generic_name":["ACETAMINOPHEN"],"is_original_packager":[true],"manufacturer_name":["Dr. Reddy's Laboratories Inc."],"package_ndc":["75907-430-01","75907-430-40"],"product_ndc":["75907-430"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1148399"],"spl_id":["2b89d8dc-aa00-5564-20a9-269c26d7d14f"],"spl_set_id":["8e780c23-997c-b960-226e-954037baad4b"],"substance_name":["ACETAMINOPHEN"],"unii":["362O9ITL9D"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL NDC 75907-430-40 8 HR Arthritis Pain Acetaminophen Extended-Release Tablets USP, 650 mg Pain Reliever / Fever Reducer For the Temporary Relief of Minor Arthritis Pain See New Warning 400 Caplets** 650 mg each (**Capsule-Shaped Bi-layer Tablets)"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding ask a health professional before use."],"purpose":["PURPOSE Pain reliever/fever reducer"],"questions":["QUESTIONS OR COMMENTS? call 1-888-375-3784 weekdays (8 AM to 8 PM EST)"],"set_id":"8e780c23-997c-b960-226e-954037baad4b","spl_product_data_elements":["8 HR Arthritis Pain ACETAMINOPHEN MAGNESIUM STEARATE CELLULOSE, MICROCRYSTALLINE POLYETHYLENE GLYCOL 400 POVIDONE K30 STARCH, CORN SODIUM STARCH GLYCOLATE TYPE A CORN STEARIC ACID ACETAMINOPHEN ACETAMINOPHEN HYDROXYETHYL CELLULOSE (140 MPA.S AT 5%) HYPROMELLOSE 2910 (6 MPA.S) G650 Container label"],"spl_unclassified_section":["OTHER INFORMATION • store between 20-25°C (68-77°F) • do not use if foil inner seal is broken or missing."],"stop_use":["Stop use and ask doctor if • pain gets worse or lasts more than 10 days • fever gets worse or lasts more than 3 days • new symptoms occur • redness or swelling is present These could be signs of a serious condition."],"version":"1","warnings":["WARNINGS Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take • more than 6 caplets in 24 hours, which is the maximum daily amount • with other drugs containing acetaminophen • 3 or more alcoholic drinks everyday while using this product Allergy alert: acetaminophen may cause severe skin reactions Symptoms may include: • skin reddening • blisters • rash If a skin reaction occurs, stop use and seek medical help right away"]}