{"active_ingredient":["Anhydrous citric acid 1000 mg Sodium bicarbonate (heat-treated) 1976 mg"],"ask_doctor":["Ask a doctor before use if you have a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are presently taking a prescription drug. Antacids may interact with certain prescription drugs."],"do_not_use":["Do not use if you have ever had an allergic reaction to this product or any of its ingredients"],"dosage_and_administration":["Directions ● fully dissolve 2 tablets in 4 ounces of water before taking adults and children 12 years and over 2 tablets every 4 hours as needed, or as directed by a doctor do not exceed 8 tablets in 24 hours adults 60 years and over 2 tablets every 4 hours as needed, or as directed by a doctor do not exceed 4 tablets in 24 hours children under 12 years consult a doctor"],"dosage_and_administration_table":["<table border=\"0\" width=\"100%\"><tbody><tr><td>adults and children 12 years and over</td><td>2 tablets every 4 hours as needed, or as directed by a doctor</td><td>do not exceed 8 tablets in 24 hours</td></tr><tr><td>adults 60 years and over</td><td>2 tablets every 4 hours as needed, or as directed by a doctor</td><td>do not exceed 4 tablets in 24 hours</td></tr><tr><td>children under 12 years</td><td>consult a doctor</td><td/></tr></tbody></table>"],"effective_time":"20250311","id":"30155636-9069-f8ae-e063-6394a90a54a4","inactive_ingredient":["Inactive ingredients magnesium stearate, mannitol"],"indications_and_usage":["Uses for the relief of heartburn acid indigestion sour stomach upset stomach associated with these symptoms"],"keep_out_of_reach_of_children":["Keep out of reach of children."],"openfda":{"application_number":["M001"],"brand_name":["Alka-Seltzer Heartburn Relief Extra Strength"],"generic_name":["ANHYDROUS CITRIC ACID, SODIUM BICARBONATE (HEAT-TREATED)"],"is_original_packager":[true],"manufacturer_name":["Bayer Healthcare LLC"],"package_ndc":["0280-0079-01","0280-0079-02","0280-0079-03"],"product_ndc":["0280-0079"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["2571087"],"spl_id":["30155636-9069-f8ae-e063-6394a90a54a4"],"spl_set_id":["dc1641f8-54c2-0d86-e053-2995a90a1dce"],"substance_name":["SODIUM BICARBONATE","CITRIC ACID MONOHYDRATE"],"unii":["8MDF5V39QO","2968PHW8QP"]},"other_safety_information":["Other information ● each tablet contains: sodium 586 mg ● store at room temperature. Avoid excessive heat. ● Alka-Seltzer Extra Strength in water contains the antacid sodium citrate as the principal active ingredient"],"package_label_principal_display_panel":["​ALKA-SELTZER Fast 4-in-1 Relief of: Heartburn Sour Stomach Acid Indigestion Upset Stomach HEARTBURN RELIEF EXTRA STRENGTH 24 EFFERVESCENT TABLETS (12 - 2 count pouches) AlkaSeltzerHRES"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Antacid Antacid"],"questions":["Questions or comments? 1-800-986-0369 (Mon – Fri 9AM – 5PM EST)"],"set_id":"dc1641f8-54c2-0d86-e053-2995a90a1dce","spl_product_data_elements":["Alka-Seltzer Heartburn Relief Extra Strength Anhydrous citric acid, Sodium bicarbonate (heat-treated) MAGNESIUM STEARATE MANNITOL SODIUM BICARBONATE SODIUM CATION CITRIC ACID MONOHYDRATE ANHYDROUS CITRIC ACID ALKA;SELTZER;EX;S"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if you have taken the maximum dose for 2 weeks"],"version":"10","warnings":["Warnings"],"when_using":["When using this product do not exceed recommended dosage"]}