{"active_ingredient":["Active ingredient s Carboxymethylcellulose sodium 0.5% Glycerin 0.9%"],"dosage_and_administration":["Directions Prior to first use, please read the “Instructions For Use” inside this carton. Instill 1 or 2 drops in the affected eye(s) as needed."],"effective_time":"20260424","id":"309c2158-e21b-49f6-861f-a6011a9257c0","inactive_ingredient":["Inactive ingredients Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate."],"indications_and_usage":["Uses For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation."],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M018"],"brand_name":["REFRESH TEARS PF"],"generic_name":["CARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN"],"is_original_packager":[true],"manufacturer_name":["Allergan, Inc."],"nui":["N0000185370","N0000175629","N0000184306","N0000185001","M0000728","M0009417"],"package_ndc":["0023-3110-10","0023-3110-35","0023-3110-50"],"pharm_class_cs":["Allergens [CS]","Glycerol [CS]"],"pharm_class_epc":["Non-Standardized Chemical Allergen [EPC]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]"],"product_ndc":["0023-3110"],"product_type":["HUMAN OTC DRUG"],"route":["OPHTHALMIC"],"rxcui":["1100650"],"spl_id":["309c2158-e21b-49f6-861f-a6011a9257c0"],"spl_set_id":["9e1cba7b-84ed-47f3-b19a-121992834350"],"substance_name":["CARBOXYMETHYLCELLULOSE SODIUM","GLYCERIN"],"unii":["K679OBS311","PDC6A3C0OX"]},"other_safety_information":["Other information Use only if tape seals on top and bottom flaps are intact. Use before expiration date marked on container. Discard 90 days after opening. Store at 59°-77°F (15°-25°C). RETAIN THIS CARTON AND THE INSERT FOR FUTURE REFERENCE."],"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL NDC 0023-3110-10 PRESERVATIVE - FREE Refresh Tears ® PF Lubricating Eye Drops NDC 0023-3110-10 PRESERVATIVE-FREE Refresh Tears® PF Lubricating Eye Drops"],"purpose":["Purpose Eye lubricant Eye lubricant"],"questions":["Questions or comments? 1.800. 6 78 . 1605 refresh eyedrops .com v3.0DFL3110"],"set_id":"9e1cba7b-84ed-47f3-b19a-121992834350","spl_product_data_elements":["REFRESH TEARS PF carboxymethylcellulose sodium, Glycerin CARBOXYMETHYLCELLULOSE SODIUM CARBOXYMETHYLCELLULOSE GLYCERIN GLYCERIN BORIC ACID CALCIUM CHLORIDE ERYTHRITOL LEVOCARNITINE MAGNESIUM CHLORIDE POTASSIUM CHLORIDE WATER SODIUM BORATE TRISODIUM CITRATE DIHYDRATE"],"stop_use":["Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours."],"version":"5","warnings":["Warnings For external use only. To avoid contamination, do not touch tip of container to any surface. Replace cap after using. If solution changes color or becomes cloudy , do not use. Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."]}