{"active_ingredient":["Active ingredients (in each pill) Caffeine, 50 mg Magnesium Salicylate (NSAID)*, 162.5 mg (Present as 202 mg of the Tetrahydrate) *Non-steroidal anti-inflammatory drug"],"ask_doctor":["Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis or kidney disease you are taking a diuretic."],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking a prescription drug for diabetes, gout or arthritis taking any other drug"],"do_not_use":["Do not use if you have ever had an allergic reaction to any other pain reliever/fever reducer."],"dosage_and_administration":["Directions Read all package directions and warnings before use and use only as directed. Adults: Two (2) pills every 4 to 6 hours while symptoms persist, not to exceed eight (8) pills per day. Start taking 5 or 6 days before onset of period and continue until desired relief is obtained or end of period. Drink 6 to 8 glasses of water daily. For use by normally healthy adults only. Persons under 18 years of age should use only as directed by a doctor. Note: DIUREX Water Pills will not discolor urine."],"effective_time":"20250410","id":"32732994-0e5d-93a9-e063-6394a90a9c50","inactive_ingredient":["Inactive ingredients Acacia, calcium carbonate, corn starch, crospovidone, FD&C Blue #1 Lake, hypromellose, magnesium stearate, maltodextrin, microcrystalline cellulose, mineral oil, polyethylene glycol, polysorbate 80, silica, sodium starch glycolate, stearic acid, talc, titanium dioxide, triacetin."],"indications_and_usage":["Uses For temporary relief of temporary water retention bloat swelling full feeling fatigue minor aches and pains associated with the premenstrual and menstrual periods."],"information_for_patients":["Other information Magnesium content: 15 mg/pill, Calcium content: 10 mg/pill **Contents sealed: Each DIUREX blue colored, round shaped pill bears the identifying mark “ALVA\" and is sealed in a clear plastic blister with a foil backing. Do not use if seal appears broken or if product contents do not match product description. You may report serious side effects to the phone number provided under Questions? below."],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a poison control center right away."],"openfda":{"application_number":["M027"],"brand_name":["Diurex Water Pills"],"generic_name":["CAFFEINE, MAGNESIUM SALICYLATE"],"is_original_packager":[true],"manufacturer_name":["Kobayashi Healthcare International, Inc."],"nui":["N0000175739","N0000175729","N0000175790","M0023046"],"package_ndc":["52389-306-01","52389-306-84","52389-306-42","52389-306-02","52389-306-22","52389-306-21","52389-306-36"],"pharm_class_cs":["Xanthines [CS]"],"pharm_class_epc":["Central Nervous System Stimulant [EPC]","Methylxanthine [EPC]"],"pharm_class_pe":["Central Nervous System Stimulation [PE]"],"product_ndc":["52389-306"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1001437"],"spl_id":["32732994-0e5d-93a9-e063-6394a90a9c50"],"spl_set_id":["e02a39f9-1c8c-4d38-b394-3f5b7062932c"],"substance_name":["MAGNESIUM SALICYLATE","CAFFEINE"],"unii":["41728CY7UX","3G6A5W338E"],"upc":["0072959065423"]},"package_label_principal_display_panel":["PDP"],"pregnancy_or_breast_feeding":["If pregnant or breastfeeding, ask a health professional before use."],"purpose":["Purpose Diuretic Analgesic (pain reliever)"],"questions":["Questions? 1-800-792-2582"],"set_id":"e02a39f9-1c8c-4d38-b394-3f5b7062932c","spl_product_data_elements":["Diurex Water Pills Caffeine, magnesium salicylate ACACIA CALCIUM CARBONATE STARCH, CORN CROSPOVIDONE FD&C BLUE NO. 1 HYPROMELLOSES MAGNESIUM STEARATE MALTODEXTRIN CELLULOSE, MICROCRYSTALLINE LIGHT MINERAL OIL POLYETHYLENE GLYCOL 400 POLYSORBATE 80 SILICON DIOXIDE SODIUM STARCH GLYCOLATE TYPE A POTATO STEARIC ACID TALC TITANIUM DIOXIDE TRIACETIN MAGNESIUM SALICYLATE SALICYLIC ACID CAFFEINE CAFFEINE ALVA"],"spl_unclassified_section":["Diurex Water Pills Spanish Drug Facts"],"stop_use":["Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. pain gets worse or lasts more than 10 days. fever gets worse or lasts more than 3 days. redness or swelling is present. ringing in the ears or loss of hearing occurs. any new symptoms appear. you experience any of the following signs of stomach bleeding: feel faint vomit blood have bloody or black stools have stomach pain that does not get better."],"version":"13","warnings":["Warnings Reye's Syndrome: Children and teenagers should not use this product for chicken pox or flu symptoms before a doctor is consulted about Reye's Syndrome, a rare but serious illness reported to be associated with aspirin. Allergy alert: Magnesium Salicylate may cause a severe allergic reaction which may include: hives facial swelling asthma (wheezing) shock Stomach bleeding warning: This product contains a non-steroidal anti-inflammatory drug (NSAID), which may cause severe stomach bleeding. The chance is higher if you are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs [aspirin, ibuprofen, naproxen or others] have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directed."],"when_using":["When using this product, limit the use of caffeine containing medications, foods or beverages because too much caffeine may cause: nervousness irritability sleeplessness occasional rapid heart beat The recommended dose of this product contains about as much caffeine as one cup of coffee."]}