{"active_ingredient":["Active ingredient (in each caplet) Acetaminophen 650 mg"],"ask_doctor":["Ask a doctor before use if you have liver disease"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin"],"do_not_use":["Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are allergic to acetaminophen or any of the inactive ingredients in this product"],"dosage_and_administration":["Directions Do not take more than directed. See overdose warning adults take 2 caplets every 8 hours with water swallow whole; do not crush, chew, split, or dissolve do not take more than 6 caplets in 24 hours do not use for more than 10 days unless directed by a doctor under 18 years of age ask a doctor"],"dosage_and_administration_table":["<table border=\"0\" width=\"100%\"><tbody><tr><td>adults</td><td><list listType=\"unordered\"><item>take 2 caplets every 8 hours with water</item><item>swallow whole; do not crush, chew, split, or dissolve</item><item>do not take more than 6 caplets in 24 hours</item><item>do not use for more than 10 days unless directed by a doctor</item></list></td></tr><tr><td>under 18   years of age </td><td><list listType=\"unordered\"><item>ask a doctor</item></list></td></tr></tbody></table>"],"effective_time":"20250622","id":"383635e0-836f-50c8-e063-6394a90a28bf","inactive_ingredient":["Inactive ingredients carnauba wax, hydroxyethyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, sodium starch glycolate, titanium dioxide, triacetin"],"indications_and_usage":["Uses temporarily relieves minor aches and pains due to: - minor pain of arthritis - muscular aches n backache - premenstrual and menstrual cramps - the common cold n headache - toothache temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children."],"openfda":{"application_number":["ANDA215486"],"brand_name":["8HR Arthritis Pain Relief"],"generic_name":["ACETAMINOPHEN"],"is_original_packager":[true],"manufacturer_name":["LEADER/ Cardinal Health 110, Inc."],"package_ndc":["70000-0733-1","70000-0733-2"],"product_ndc":["70000-0733"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1148399"],"spl_id":["383635e0-836f-50c8-e063-6394a90a28bf"],"spl_set_id":["331f907a-0fb6-e23d-e063-6394a90a2db1"],"substance_name":["ACETAMINOPHEN"],"unii":["362O9ITL9D"]},"other_safety_information":["Other information store between 20-25°C (68-77°F) The FDA approved dissolution methods differ from USP"],"overdosage":["Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"package_label_principal_display_panel":["apap-50s-label apap-50s-ifc lc-apap-label-100s lc-apap-ifc-100s"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purpose Pain reliever/ fever reducer"],"questions":["Questions or comments? Call 1-877-290-4008"],"set_id":"331f907a-0fb6-e23d-e063-6394a90a2db1","spl_product_data_elements":["8HR Arthritis Pain Relief Acetaminophen MICROCRYSTALLINE CELLULOSE HYDROXYETHYL CELLULOSE (140 CPS AT 5%) MAGNESIUM STEARATE ACETAMINOPHEN ACETAMINOPHEN CARNAUBA WAX TITANIUM DIOXIDE TRIACETIN POVIDONE STARCH, CORN SODIUM STARCH GLYCOLATE TYPE A HYPROMELLOSE, UNSPECIFIED (Capsule-Shaped Tablet) (White to off white) 71"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present These could be signs of a serious condition"],"version":"3","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 6 caplets in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include: - skin reddening - blisters - rash If a skin reaction occurs, stop use and seek medical help right away."]}