{"dosage_and_administration":["Directions section Directions: Adults and children 12 years of age and older: Rub a thin thin film over not more than 4 times daily mass; massage not necessary Children under 12 years of age: Consult physician"],"effective_time":"20250728","id":"3b01b609-19ac-bc80-e063-6294a90acad1","inactive_ingredient":["Inactive Ingredients: Alcohol, Aloe Barbadensis Leaf Extract, Arnica Montana Flower Extract, Boswellia Carterii Resin Extract, Camellia Sinensis Leaf Extract, Camphor, Carbomer, FD&C Blue No. 1, FD&C Yellow No. 5, Glycerin, Ilex Paraguariensis Leaf Extract, Isopropyl Myristate, Silica, Triethanolamine, Vitamin E, Water."],"indications_and_usage":["Uses Uses: Temporary relief from minor aches and pains of sore muscles and joints associated with arthritis, backache, strains and sprains"],"keep_out_of_reach_of_children":["Keep out of reach of children Keep out of reach of children: If accidentally ingested, get medical help or contact a Poison Control Center immediately"],"openfda":{"application_number":["M017"],"brand_name":["SYNC ICE"],"generic_name":["SYNC RELIEF ICE"],"is_original_packager":[true],"manufacturer_name":["iON Pharma, LLC"],"package_ndc":["82944-300-74"],"product_ndc":["82944-300"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["415974"],"spl_id":["3b01b609-19ac-bc80-e063-6294a90acad1"],"spl_set_id":["38ce98ce-a7bf-8041-e063-6394a90ae730"],"substance_name":["MENTHOL"],"unii":["L7T10EIP3A"],"upc":["0382944300744"]},"package_label_principal_display_panel":["NDC 82944-300-74 sync RELIEF ICE Relief in Motion COLD THERAPY PAIN RELIEF PAIN RELIEF GEL ROLL-ON PARABEN-FREE FOR SORE MUSCLES, BACKACHES, SORE JOINTS & ARTHRITIS 2.5 FL. OZ. / 74 ml www.syncrelief.com Does not contain NSAIDs, Ibuprofen, Salicylate Sync Relief Ice Sync Relief Ice Label"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding section If pregnant or breast-feeding: Ask a healthcare professional before use"],"purpose":["Drug facts Active ingredient Drug facts Active ingredient: purpose Menthol 4% Topical Analgesic"],"questions":["Questions comments section Questions or Comments: 833.711.8833 info@syncrelief.com"],"set_id":"38ce98ce-a7bf-8041-e063-6394a90ae730","spl_product_data_elements":["SYNC ICE Sync Relief ICE ALCOHOL 95% ALOE BARBADENSIS LEAF SILICA TRIETHANOLAMINE ALPHA-TOCOPHEROL WATER GLYCERIN MENTHOL MENTHOL FD&C YELLOW NO. 5 FD&C BLUE NO. 1 CAMPHOR (NATURAL) CARBOMER ARNICA MONTANA FLOWER CAMELLIA SINENSIS LEAF ILEX PARAGUARIENSIS LEAF ISOPROPYL MYRISTATE BOSWELLIA CARTERII OIL"],"stop_use":["Stop use section Stop use and ask a doctor if: Condition worsens, or if symptoms persist for more than 7 days, or clear up and reoccur"],"version":"2","warnings":["Warnings Warnings: For external use only Flammable: Keep away from excessive heat or open flame Ask a doctor before use if you have: Sensitive skin"],"when_using":["When using this product When using this product: Avoid contact with eyes or mucous membranes Do not apply to wounds or damaged skin Do not use with other ointments, creams, sprays or liniments Do no apply to irritated skin or if excessive irritation develops Do not bandage Wash hands after use with cool water Do not use with heating pad or decide Store in a cool dry place"]}