{"active_ingredient":["Active ingredient (in each tablet) Aspirin (NSAID*) 325 mg Citric Acid 1000 mg Sodium bicarbonate (heat-treated) 1916 mg *nonsteriodal anti-inflammatory drug"],"ask_doctor":["Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you are on a sodium restricted diet you reached age 60 or older"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking any other drugs (prescription or non-prescription). Antacids may interact with certain drugs. under a doctor's care for any serious condition"],"do_not_use":["Do not use if you have ever had an allergic reaction to any other pain reliever/ fever reducer if you are taking a prescription drug for gout, diabetes or arthritis"],"dosage_and_administration":["Directions do not exceed recommended dosage to avoid serious injury, completely dissolve tablets in 4 oz. of water before taking Adults and children 12 to 60 years of age: 2 tablets every 4 hours. Do not exceed 8 tablets in 24 hours or do not use the maximum dosage for more than 10 days. Children under 12 years of age: Do not give to children under 12 years of age. 60 years and older: Do not exceed 4 tablets in 24 hours or do not use the maximum dosage for more than 10 days."],"effective_time":"20250819","id":"3cb9b823-c883-264e-e063-6294a90a008b","inactive_ingredient":["none"],"indications_and_usage":["Uses For the temporary relief of heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains upset stomach with headache from overindulgence in food or drink headache, body aches, and pain alone"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M013"],"brand_name":["Medique Medi Seltzer"],"generic_name":["ASPIRIN, CITRIC ACID, SODIUM BICARBONATE"],"is_original_packager":[true],"manufacturer_name":["Unifirst First Aid Corporation"],"nui":["N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["47682-135-20","47682-135-24","47682-135-60"],"pharm_class_cs":["Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["47682-135"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1536675"],"spl_id":["3cb9b823-c883-264e-e063-6294a90a008b"],"spl_set_id":["528da9d9-2a52-4c16-b7b2-61b3eee1abea"],"substance_name":["ASPIRIN","CITRIC ACID MONOHYDRATE","SODIUM BICARBONATE"],"unii":["R16CO5Y76E","2968PHW8QP","8MDF5V39QO"],"upc":["0347682135249"]},"other_safety_information":["Other information each tablet contains: Sodium 524 mg store at room temperature 59º-86º F (15º-30º C) read all product information before using avoid excessive heat and humidity tamper evident sealed packets do not use any opened or torn packets"],"package_label_principal_display_panel":["Medique Medi-Seltzer Label Medique® Medi-Seltzer Effervescent Antacid/Pain Reliever Pull to Open This Package is for Households without Young Children. Aches, Fever ● Aspirin (NSAID) 325 mg Antacid ● Citric Acid 1000 mg Sodium Bicarbonate 1916 mg 72 Tablets (36 x 2) Tamper Evident Unit Dose Packets Medique"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin (*NSAIDS) at 20 weeks or later in pregnancy unless specifically directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":["Purpose Pain reliever /fever reducer Antacid Antacid"],"questions":["Questions or comments? 1-800-634-7680"],"set_id":"528da9d9-2a52-4c16-b7b2-61b3eee1abea","spl_product_data_elements":["Medique Medi Seltzer aspirin, citric acid, sodium bicarbonate ASPIRIN ASPIRIN CITRIC ACID MONOHYDRATE ANHYDROUS CITRIC ACID SODIUM BICARBONATE BICARBONATE ION white ROUND L421"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if you experience any of the following signs of stomach bleeding: you feel faint vomit blood have bloody or black stools have stomach pain that does not get better pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days you have difficulty swallowing ringing in the ears or loss of hearing occurs redness or swelling is present in the painful area any new symptoms appear"],"version":"13","warnings":["Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include: hives facial swelling asthma (wheezing) shock If an allergic reaction occurs, stop use and seek medical help right away. Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcohol drinks every day while using this product take more or for a longer time than directed"],"when_using":["When using this product do not exceed recommended dosage."]}