{"active_ingredient":["Active Ingredients (in each effervescent tablet) Buffered aspirin 325 mg (NSAID)* *nonsteroidal anti-inflammatory drug"],"ask_doctor":["Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma you have a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking a prescription drug for: diabetes gout arthritis"],"do_not_use":["Do not use if you are allergic to aspirin or any other pain reliever/ fever reducer if you have ever had an allergic reaction to this product or any of its ingredients"],"dosage_and_administration":["Directions do not exceed recommended dosage to avoid serious injury, completely dissolve tablets in 4 oz. of water before taking. Adults and children 12 years and over: 2 tablets every 4 hours, or as directed by a doctor. Do not exceed 8 tablets in 24 hours Adults 60 years and over: 2 tablets every 4 hours, or as directed by a doctor. Do not exceed 4 tablets in 24 hours Children under 12 years of age: Consult a doctor"],"effective_time":"20250908","id":"3e4cc924-d005-c86b-e063-6394a90accd9","inactive_ingredient":["Inactive ingredients : anhydrous citric acid, sodium bicarbonate"],"indications_and_usage":["Uses for the temporary relief of minor aches and pains due to: headache muscle pain backache toothache menstrual pain colds minor arthritis pain temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M013"],"brand_name":["Medique Medi-Seltzer Pain Relief"],"generic_name":["ASPIFIN"],"is_original_packager":[true],"manufacturer_name":["Unifirst First Aid Corporation"],"nui":["N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["47682-147-20","47682-147-24"],"pharm_class_cs":["Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["47682-147"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["2606079"],"spl_id":["3e4cc924-d005-c86b-e063-6394a90accd9"],"spl_set_id":["3d593dee-b932-b611-e063-6294a90ad3b7"],"substance_name":["ASPIRIN"],"unii":["R16CO5Y76E"],"upc":["0347682165345"]},"other_safety_information":["Other information each tablet contains: Sodium 524mg store at room temperature 59º-86º F (15º-30º C) avoid excessive heat. tamper evident sealed packets do not use any opened or torn packets"],"package_label_principal_display_panel":["Medique® Medi-Seltzer Pain Relief Effervescent Antacid / Pain Reliever Pull to Open This Package is for Households without Young Children. Aches, Fever ● Aspirin (NSAID) 325 mg Antacid ● Citric Acid 1000 mg Sodium Bicarbonate 1916 mg 36 Tablets (18 x 2) Tamper Evident Unit Dose Packets 125B MedSeltzerPain 12520 3-17-25"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy, unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":["Purpose Pain Reliever / Fever Reducer"],"questions":["Questions or comments? 1-800-634-7680"],"set_id":"3d593dee-b932-b611-e063-6294a90ad3b7","spl_product_data_elements":["Medique Medi-Seltzer Pain Relief Aspifin ASPIRIN ASPIRIN CITRIC ACID MONOHYDRATE SODIUM BICARBONATE L421"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if you experience any of the following signs of stomach bleeding you feel faint vomit blood have bloody or black stools have stomach pain that does not get better an allergic reaction occurs. Seek medical help right away pain lasts for more than 10 days or gets worse fever gets worse or lasts more than 3 days new symptoms appear redness or swelling is present ringing in the ears or a loss of hearing occurs"],"version":"2","warnings":["Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy Alert: Aspirin may cause a severe allergic reaction which may include: hives facial swelling asthma (wheezing) shock Stomach bleeding warning : This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directed"],"when_using":["When using this product do not take exceed recommended dosage"]}