{"active_ingredient":["Active ingredient (in each caplet) Acetaminophen 500 mg Pamabrom 25 mg Pyrilamine maleate 15 mg"],"ask_doctor":["Ask a doctor before use if you have ■ difficulty in urination due to enlargement of the prostate gland ■ a breathing problem such as emphysema or chronic bronchitis ■ liver disease ■ glaucoma"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are ■ taking sedatives or tranquilizers ■ taking the blood thinning drug warfarin"],"do_not_use":["Do not use ■ with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ■ if you have ever had an allergic reaction to this product or any of its ingredients"],"dosage_and_administration":["Directions ■ do not take more than directed Adults and children: (12 years and over) ■ take 2 caplets with water every 6 hours as needed ■ do not exceed 6 caplets in a 24 hour period or as directed by a doctor Children under 12 years: ask a doctor"],"effective_time":"20250909","id":"3e5d5132-9c04-1a98-e063-6394a90a6a9c","inactive_ingredient":["Inactive ingredients corn starch, croscarmellose sodium, crospovidone, FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, shellac wax, silicon dioxide, stearic acid, talc, titanium dioxide"],"indications_and_usage":["Uses for the temporary relief of these symptoms associated with menstrual periods: ■ headache ■ bloating ■ cramps ■ backache ■ muscular aches ■ irritability ■ water-weight gain"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of accidental overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{"application_number":["M027"],"brand_name":["Medi First Plus PMS Relief","Medi First PMS Relief"],"generic_name":["ACETAMINOPHEN, PAMABROM, PYRILAMINE MALEATE"],"is_original_packager":[true],"manufacturer_name":["Unifirst First Aid Corporation"],"package_ndc":["47682-823-99","47682-823-80","47682-823-36","47682-723-80","47682-723-36"],"product_ndc":["47682-723","47682-823"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1052637"],"spl_id":["3e5d5132-9c04-1a98-e063-6394a90a6a9c"],"spl_set_id":["e84007e7-498d-4662-e053-2995a90ad4de"],"substance_name":["PAMABROM","PYRILAMINE MALEATE","ACETAMINOPHEN"],"unii":["UA8U0KJM72","R35D29L3ZA","362O9ITL9D"],"upc":["0347682923808","0347682823801"]},"other_safety_information":["Other information ■ store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) ■ tamper-evident sealed packets ■ do not use any opened or torn packets"],"package_label_principal_display_panel":["Medi-First® PMS Relief Pain Reliever • Acetaminophen 500 mg Diuretic • Pamabrom 25 mg Antihistamine • Pyrilamine maleate 15 mg Mestrual Pain Relief Pull to Open This Package is for Households Without Young Children. Tamper Evident Unit Dose Packets 80 Caplets (40 x 2) 823R MF PMS","Medi-First®Plus PMS Relief Pain Reliever • Acetaminophen 500 mg Diuretic • Pamabrom 25 mg Antihistamine • Pyrilamine maleate 15 mg This Package is for Households Without Young Children. Pull to Open Relief from Menstrual Pain, Water Retention and Bloating Tamper Evident Unit Dose Packets 80 Caplets (40 x 2's) 823RMFP PMS"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purpose Pain reliever Diuretic Antihistamine"],"questions":["Questions or comments? 1-800-634-7680"],"set_id":"e84007e7-498d-4662-e053-2995a90ad4de","spl_product_data_elements":["Medi First PMS Relief Acetaminophen, Pamabrom, Pyrilamine maleate PAMABROM BROMOTHEOPHYLLINE PYRILAMINE MALEATE PYRILAMINE POVIDONE, UNSPECIFIED SILICON DIOXIDE ACETAMINOPHEN ACETAMINOPHEN CROSCARMELLOSE SODIUM FD&C BLUE NO. 2--ALUMINUM LAKE POLYVINYL ALCOHOL, UNSPECIFIED TITANIUM DIOXIDE MAGNESIUM STEARATE TALC CROSPOVIDONE STEARIC ACID SHELLAC STARCH, CORN FD&C RED NO. 40 MICROCRYSTALLINE CELLULOSE POLYETHYLENE GLYCOL, UNSPECIFIED 44;679 Caplet Medi First Plus PMS Relief Acetaminophen, Pamabrom, Pyrilamine maleate PAMABROM BROMOTHEOPHYLLINE PYRILAMINE MALEATE PYRILAMINE POVIDONE, UNSPECIFIED SILICON DIOXIDE ACETAMINOPHEN ACETAMINOPHEN CROSCARMELLOSE SODIUM FD&C BLUE NO. 2--ALUMINUM LAKE POLYVINYL ALCOHOL, UNSPECIFIED TITANIUM DIOXIDE MAGNESIUM STEARATE TALC CROSPOVIDONE STEARIC ACID SHELLAC STARCH, CORN FD&C RED NO. 40 MICROCRYSTALLINE CELLULOSE POLYETHYLENE GLYCOL, UNSPECIFIED 44;679 Caplet"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if ■ pain gets worse or lasts more than 10 days ■ fever gets worse or lasts more than 3 days ■ new symptoms occur ■ redness or swelling is present These could be signs of a serious condition."],"version":"5","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take ■ more than 4,000 mg of acetaminophen in 24 hours ■ with other drugs containing acetaminophen ■ 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away."],"when_using":["When using this product ■ drowsiness may occur ■ avoid alcoholic beverages ■ excitability may occur, especially in children ■ alcohol, sedatives and tranquilizers may increase drowsiness ■ use caution when driving a motor vehicle or operating machinery"]}