{"active_ingredient":["Active ingredient (in each tablet) Acetaminophen 500 mg"],"ask_doctor":["Ask a doctor before use if you have liver disease"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin"],"do_not_use":["Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. for more than 10 days for pain unless directed by a doctor for more than 3 days for fever unless directed by a doctor"],"dosage_and_administration":["Directions do not use more than directed Adults and children: (12 years and older) Take 2 tablets every 4 to 6 hours as needed. Do not take more than 8 tablets in 24 hours. Children under 12 years: Do not give this adult strength product to children under 12 years of age; this will provide more than the recommended dose (overdose) and may cause liver damage."],"effective_time":"20250909","id":"3e5d7595-9e65-3fd6-e063-6394a90a6f80","inactive_ingredient":["Inactive ingredients corn starch, hypromellose, maltodextrin*, microcrystalline cellulose*, polyethylene glycol, povidone*, pregelatinized starch*, sodium starch glycolate*, stearic acid, titanium dioxide*. * may contain"],"indications_and_usage":["Uses For the temporary relief of minor aches and pains associated with headache muscular aches minor arthritis pain common cold toothache menstrual cramps For the reduction of fever."],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of accidental overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{"application_number":["M013"],"brand_name":["Direct Safety Extra Strength Aspirin Free"],"generic_name":["ACETAMINOPHEN"],"is_original_packager":[true],"manufacturer_name":["Conney Safety Products, LLC"],"package_ndc":["61245-175-13","61245-176-13"],"product_ndc":["61245-175","61245-176"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["198440"],"spl_id":["3e5d7595-9e65-3fd6-e063-6394a90a6f80"],"spl_set_id":["a524c36a-38f3-4266-8f45-589e19400328"],"substance_name":["ACETAMINOPHEN"],"unii":["362O9ITL9D"]},"package_label_principal_display_panel":["175 Direct Safety XS Aspirin Free Direct Safety® Extra Strength Aspirin-Free Pain Reliever/Fever Reducer Acetaminophen 500 mg. Acetaminofeno 500 mg. Industrial Pack 500 (250 Packets of 2 Tablets) 175R DS EXS Aspirin Free","176 Direct Safety XS Aspirin Free Label Direct Safety® Extra Strength Aspirin Free Aspirin-Free Pain Reliever/Fever Reducer Acetaminophen 500 mg. Acetaminofeno 500 mg. Industrial Pack 500 (250 Packets of 2 Tablets) 175 XS Aspirin Free"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purpose Pain reliever/fever reducer"],"questions":["Questions or comments? 1-800-356-9100"],"set_id":"a524c36a-38f3-4266-8f45-589e19400328","spl_product_data_elements":["Direct Safety Extra Strength Aspirin Free Acetaminophen HYPROMELLOSES POLYETHYLENE GLYCOL, UNSPECIFIED POVIDONE SODIUM STARCH GLYCOLATE TYPE A POTATO STARCH, CORN STEARIC ACID TITANIUM DIOXIDE ACETAMINOPHEN ACETAMINOPHEN white ROUND AZ;235 Direct Safety Extra Strength Aspirin Free Acetaminophen CELLULOSE, MICROCRYSTALLINE HYPROMELLOSES MALTODEXTRIN POLYETHYLENE GLYCOL, UNSPECIFIED POVIDONE SODIUM STARCH GLYCOLATE TYPE A CORN STARCH, CORN STEARIC ACID ACETAMINOPHEN ACETAMINOPHEN ROUND FR;33 white"],"spl_unclassified_section":["Drug Facts","Other information store at room temperature 59º-86ºF (15º-30ºC) tamper-evident sealed packets do not use any opened or torn packets"],"stop_use":["Stop using and ask a doctor if symptoms do not improve new symptoms occur pain or fever persists or gets worse redness or swelling is present"],"version":"11","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 8 tablets in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. for more than 10 days for pain unless directed by a doctor for more than 3 days for fever unless directed by a doctor Ask a doctor before use if you have liver disease Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin Stop using and ask a doctor if symptoms do not improve new symptoms occur pain or fever persists or gets worse redness or swelling is present If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of accidental overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."]}