{"active_ingredient":["Active ingredients Sodium fluoride (0.24%)"],"dosage_and_administration":["Directions do not swallow supervise children as necessary until capable of using without supervision adults and children 2 years and older brush teeth thoroughly after meals or at least twice a day, or use as directed by a dentist or physician children under 6 years instruct in good brushing and rinsing habits (to minimize swallowing) children under 2 years ask a dentist or physician"],"effective_time":"20250909","id":"3e62cc44-3168-5e02-e063-6294a90a129d","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, PEG-8, sodium lauryl sulfate, SD alcohol 38-B, flavor, cellulose gum, sodium saccharin, red 33, red 40."],"indications_and_usage":["Use: Aids in the prevention of dental decay"],"keep_out_of_reach_of_children":["Warnings Keep out of reach of children under 6 years of age ."],"openfda":{"application_number":["M021"],"brand_name":["CLOSE UP Freshening with Mouthwash"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Church & Dwight Co., Inc."],"package_ndc":["10237-644-40","10237-644-60","10237-644-72","10237-644-80"],"product_ndc":["10237-644"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416783"],"spl_id":["3e62cc44-3168-5e02-e063-6294a90a129d"],"spl_set_id":["e660b0d7-4cc5-4028-bdf5-016b85899728"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["Principal Display Panel ANITCAVITY FLOURIDE TOOTHPASTE FRESH BREATH Fights bad breath while gently whitening CLOSE-UP CINNAMON BLAST NET WT. 4.0 OZ. (113g) CLOSE-UP Fresh Breath Carton"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions or comments? Call 1-800-786-5135 Monday-Friday 9am-5pm ET"],"set_id":"e660b0d7-4cc5-4028-bdf5-016b85899728","spl_product_data_elements":["CLOSE UP Freshening with Mouthwash Sodium Fluoride WATER HYDRATED SILICA PEG-8 STEARATE SORBITOL SODIUM LAURYL SULFATE ALCOHOL CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED D&C RED NO. 33 FD&C RED NO. 40 SACCHARIN SODIUM SODIUM FLUORIDE FLUORIDE ION"],"version":"11","warnings":["If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}