{"active_ingredient":["Drug Facts: Active Ingredients Glycerin 14.4% Phenylephrine HCl 0.25% Pramoxine HCl 1% Petrolatum 15%"],"ask_doctor":["Ask a doctor before use if you have: Heart disease High blood pressure Thyroid disease Diabetes Difficulty in urination due to enlargement of prostate gland"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are: Presently taking a prescription drug for high blood pressure or depression."],"dosage_and_administration":["Directions: Adults: When practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before applying cream. When first opening the tube, puncture foil seal with top end of cap. Apply externally or in the lower portion of the anal canal only. Apply to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement. For application in the lower anal canal: Remove cover from dispensing cap. Attach dispensing cap to tube. Lubricate dispensing cap well using cream from the tube, then gently insert dispensing cap partway into anus. Thoroughly cleanse dispensing cap after each use and replace cover. Children under 12 years of age: ask a doctor."],"effective_time":"20250924","id":"3f904257-3af2-2c97-e063-6294a90aecae","inactive_ingredient":["Inactive ingredients: Aloe vera leaf, butylated hydroxytoluene, cetostearyl alcohol, cetyl esters, cetyl palmitate, glyceryl monostearate, isopropyl myristate, lanolin, methylparaben, mineral oil, polysorbate 60, propylene glycol, propylparaben, purified water, sodium citrate, stearic acid, tocopherol acetate"],"indications_and_usage":["Uses For temporary relief from pain and burning Helps relieve local itching and discomfort associated with hemorrhoids Temporarily shrinks hemorrhoidal tissue Temporarily provides a coating for relief of anorectal discomforts Temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)"],"openfda":{"application_number":["M015"],"brand_name":["Hemorrhoidal Pain Relief"],"generic_name":["HEMORRHOIDAL PAIN RELIEF CREAM"],"is_original_packager":[true],"manufacturer_name":["Neilmed Pharmaceuticals Inc."],"nui":["N0000185370","N0000175629","N0000184306","N0000185001","M0000728","M0009417"],"package_ndc":["13709-335-01"],"pharm_class_cs":["Allergens [CS]","Glycerol [CS]"],"pharm_class_epc":["Non-Standardized Chemical Allergen [EPC]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]"],"product_ndc":["13709-335"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["1293649"],"spl_id":["3f904257-3af2-2c97-e063-6294a90aecae"],"spl_set_id":["374dc1c0-4243-b272-e063-6394a90a5a6b"],"substance_name":["PRAMOXINE HYDROCHLORIDE","PHENYLEPHRINE HYDROCHLORIDE","GLYCERIN","PETROLATUM"],"unii":["88AYB867L5","04JA59TNSJ","PDC6A3C0OX","4T6H12BN9U"]},"other_safety_information":["Other information: storage temperature: not to exceed 30°C (86°F). Protect from freezing.","Important: Please do not discard this printed box and any enclosed printed material. The inside final product may not have all the details you require for the ongoing use of the product."],"package_label_principal_display_panel":["Hemorrhoidal Cream"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, Ask a health professional before use."],"purpose":["Drug Facts: Purpose Protectant Vasoconstrictor Local Anesthetic Protectant"],"questions":["Questions or comments? 1 (877) 477-8633 TAMPER EVIDENT: DO NOT USE IF SEAL ON TUBE IS PUNCTURED OR MISSING"],"set_id":"374dc1c0-4243-b272-e063-6394a90a5a6b","spl_product_data_elements":["Hemorrhoidal Pain Relief Hemorrhoidal Pain Relief Cream METHYLPARABEN BUTYLATED HYDROXYTOLUENE ALPHA-TOCOPHEROL ACETATE SODIUM CITRATE PRAMOXINE HYDROCHLORIDE PRAMOXINE PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE CETYL ESTERS WATER ISOPROPYL MYRISTATE GLYCERIN GLYCERIN PETROLATUM PETROLATUM POLYSORBATE 60 ALOE VERA LEAF CETYL PALMITATE GLYCERYL MONOSTEARATE MINERAL OIL PROPYLENE GLYCOL STEARIC ACID LANOLIN PROPYLPARABEN CETOSTEARYL ALCOHOL"],"stop_use":["Stop use and ask doctor if: Bleeding occurs Condition worsens or does not improve within 7 days An allergic reaction occurs The symptom being treated does not subside or if redness, irritation, swelling, pain or other symptoms develop or increase"],"version":"2","warnings":["Warnings: For external use only"],"when_using":["When using this product: Do not exceed the recommended daily dosage unless directed by a doctor. Do not put in the rectum by using fingers or any mechanical device or applicator."]}