{"active_ingredient":["Active ingredients (in each caplet) Acetaminophen 250 mg Aspirin 250 mg (NSAID*) Caffeine 65 mg *nonsteroidal anti-inflammatory drug"],"ask_doctor":["Ask a doctor before use if • you have liver disease • stomach bleeding warning applies to you • you have a history of stomach problems, such as heartburn • you have high blood pressure, heart disease, liver cirrhosis, or kidney disease • you are taking a diuretic • you have asthma"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are • taking a prescription drug for diabetes, gout, or arthritis • taking any other drug or are under a doctor’s care for any serious condition"],"do_not_use":["Do not use • if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist."],"dosage_and_administration":["Directions • do ​not use more than directed • drink a full glass of water with each dose • adults and children 12 years of age and over: take 2 caplets every 6 hours; not more than 8 caplets in 24 hours • children under 12 years: ask a doctor"],"effective_time":"20251104","id":"42d2176d-0485-17cd-e063-6294a90a00b1","inactive_ingredient":["Inactive ingredients carnauba wax, colloidal silicon dioxide, hypromellose, microcrystalline cellulose, mineral oil, povidone, pregelatinized starch, sodium starch glycolate, stearic acid, titanium dioxid"],"indications_and_usage":["Uses temporarily relieves minor aches and pains due to: -headache -a cold -arthritis -muscular aches -toothache -premenstrual and menstrual cramps"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms"],"openfda":{"application_number":["M013"],"brand_name":["Headache Relief"],"generic_name":["ACETAMINOPHEN, ASPIRIN, CAFFEINE"],"is_original_packager":[true],"manufacturer_name":["Walmart Inc."],"nui":["N0000175739","N0000175729","N0000175790","M0023046","N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["79903-370-20","79903-370-01","79903-370-21"],"pharm_class_cs":["Xanthines [CS]","Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Central Nervous System Stimulant [EPC]","Methylxanthine [EPC]","Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Central Nervous System Stimulation [PE]","Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["79903-370"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["308297"],"spl_id":["42d2176d-0485-17cd-e063-6294a90a00b1"],"spl_set_id":["1557bd9b-3e7c-4769-e063-6394a90a9d91"],"substance_name":["ACETAMINOPHEN","CAFFEINE","ASPIRIN"],"unii":["362O9ITL9D","3G6A5W338E","R16CO5Y76E"],"upc":["0194346263646"]},"other_safety_information":["Other information • store at 20°- 25°C (68°- 77°F); excursions permitted between 15°-30°C (59°-86°F) • use by expiration date on package"],"package_label_principal_display_panel":["370R_2x100s_IFC 370R_100s_LBL 370r-headache-200-label"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":["Purposes Pain reliever Pain reliever Pain reliever aid"],"questions":["Questions or comments? Call 1-888-287-1915"],"set_id":"1557bd9b-3e7c-4769-e063-6394a90a9d91","spl_product_data_elements":["Headache Relief Acetaminophen, Aspirin, Caffeine CARNAUBA WAX MICROCRYSTALLINE CELLULOSE TITANIUM DIOXIDE STEARIC ACID POVIDONE STARCH, CORN SODIUM STARCH GLYCOLATE TYPE A CORN MINERAL OIL HYPROMELLOSES ACETAMINOPHEN ACETAMINOPHEN CAFFEINE CAFFEINE ASPIRIN ASPIRIN SILICON DIOXIDE Caplet TCL370"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if • an allergic reaction occurs. Seek medical help right away. • you experience any of the following signs of stomach bleeding: -feel faint -vomit blood -have bloody or black stools -have stomach pain that does not get better • ringing in the ears or loss of hearing occurs • painful area is red or swollen • pain gets worse or lasts for more than 10 days • fever gets worse or lasts for more than 3 days • any new symptoms occur These could be signs of a serious condition."],"version":"3","warnings":["Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: • skin reddening • blisters • rash If a skin reaction occurs, stop use and seek medical help right away. Allergy alert: Aspirin may cause a severe allergic reaction which may include: • hives • facial swelling • asthma (wheezing) • shock Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take • more than 8 caplets in 24 hours, which is the maximum daily amount • with other drugs containing acetaminophen • 3 or more alcoholic drinks every day while using this product Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you • are age 60 or older • have had stomach ulcers or bleeding problems • take a blood thinning (anticoagulant) or steroid drug • take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) • have 3 or more alcoholic drinks every day while using this product • take more or for a longer time than directed Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heartbeat."]}