{"active_ingredient":["Active ingredients (in each caplet) Acetaminophen 500 mg Caffeine 60 mg Pyrilamine maleate 15 mg"],"ask_doctor":["Ask a doctor before use if you have liver disease glaucoma difficulty un rination due to the enlargement of the prostate gland a breathing problem sucha as emphysema or chronic bronchitis"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers"],"do_not_use":["Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you have ever had an allergic reaction to this product or any of its ingredients"],"dosage_and_administration":["Directions do not exceed recommended dosage adults and children 12 years and over; take 2 caplets with water. Repeat every 6 hours, as needed. Do not exceed 6 caplets per day. children under 12 years: consult a doctor"],"effective_time":"20251112","id":"436b3716-1c88-bfba-e063-6394a90a1e12","inactive_ingredient":["Inactive ingredientes colloidal silicon dioxide, hydroxy propyl methyl cellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, pvp K-30, sodium starch glycolate, stearic acid, talc, titanium dioxide."],"indications_and_usage":["Uses for the temporary relief of these symptoms associated with menstrual periods: cramps bloating water-weight gain headache backache muscle aches fatigue"],"keep_out_of_reach_of_children":["Keep out of reach of children Keep out of reach of children"],"openfda":{"application_number":["M013"],"brand_name":["Buscapina"],"generic_name":["ACETAMINOPHEN, CAFFEINE AND PYRILAMINE MALEATE"],"is_original_packager":[true],"manufacturer_name":["OPMX LLC"],"nui":["N0000175739","N0000175729","N0000175790","M0023046"],"package_ndc":["69729-813-24"],"pharm_class_cs":["Xanthines [CS]"],"pharm_class_epc":["Central Nervous System Stimulant [EPC]","Methylxanthine [EPC]"],"pharm_class_pe":["Central Nervous System Stimulation [PE]"],"product_ndc":["69729-813"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"spl_id":["436b3716-1c88-bfba-e063-6394a90a1e12"],"spl_set_id":["436b3716-1c87-bfba-e063-6394a90a1e12"],"substance_name":["PYRILAMINE MALEATE","ACETAMINOPHEN","CAFFEINE"],"unii":["R35D29L3ZA","362O9ITL9D","3G6A5W338E"]},"other_safety_information":["Other information Store at room temperature 68-77°F (20-25°C) TAMPER EVIDENT: DO NOT USE IF PACKAGE IS OPENED OR IF BLISTER UNIT IS TORN, BROKEN OR SHOWS ANY SIGN OF TAMPERING"],"overdosage":["In case of overdose get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symtoms."],"package_label_principal_display_panel":["NDC-69729-131-24 Buscapina Acetaminophen 500 mg Caffeine 60mg Pyrilamine Maleate 15mg Pain Reliever Cramps/Cólicos Bloating/Hinchazón Fatigue/Fatiga Headache/ Dolor de cabeza Backache/Dolor de espalda 24 Caplets Buscapina 69729-813-24"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding ask a health professional before use"],"purpose":["Purpose Active ingredients (in each caplet) Purpose Acetaminophen 500 mg Pain reliever Caffeine 60 mg Diuretic Pyrilamine maleate 15 mg Antihistamine"],"purpose_table":["<table border=\"0\" width=\"100%\"><tbody><tr><td><content styleCode=\"bold\"><content styleCode=\"italics\">Active ingredients (in each caplet)</content></content></td><td><content styleCode=\"bold\"><content styleCode=\"italics\">Purpose</content></content></td></tr><tr><td>Acetaminophen 500 mg</td><td>Pain reliever</td></tr><tr><td>Caffeine 60 mg</td><td>Diuretic</td></tr><tr><td>Pyrilamine maleate 15 mg</td><td>Antihistamine</td></tr></tbody></table>"],"questions":["Questions? Call toll free 619-600-5632 Monday through Friday 9AM-5PM EST PLEASE REFER TO LEAFLET INSTRUCTUIONS IN SPANISH CONSULTE EL FOLLETO PARA INSTRUCCIONES EN ESPAÑOL"],"set_id":"436b3716-1c87-bfba-e063-6394a90a1e12","spl_product_data_elements":["Buscapina Acetaminophen, Caffeine and Pyrilamine Maleate SILICON DIOXIDE POVIDONE K30 STEARIC ACID STARCH, CORN POLYETHYLENE GLYCOL, UNSPECIFIED TALC PYRILAMINE MALEATE PYRILAMINE ACETAMINOPHEN ACETAMINOPHEN HYPROMELLOSE, UNSPECIFIED SODIUM STARCH GLYCOLATE TYPE A MICROCRYSTALLINE CELLULOSE MAGNESIUM STEARATE CAFFEINE CAFFEINE TITANIUM DIOXIDE"],"spl_unclassified_section":["Drug Facts Drug Facts"],"stop_use":["Stop use and ask a doctor if new symptoms appear redness or swelling is present pain gets worse or lasts for more than 10 days fever gets worse or lasts for more than 3 days"],"version":"1","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 6 tablets in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product. Allergy warning: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: skin reddening blisters rash hives facial swelling asthma (wheezing) shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have liver disease glaucoma difficulty un rination due to the enlargement of the prostate gland a breathing problem sucha as emphysema or chronic bronchitis Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers When using this product you may get drowsy avoid alcoholic drinks excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery limit the use of caffeine-containing medications, foods or beverages because too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally rapid heartbeat. The recommended dose of this product contains aboout as much caffeine as a cup of coffee. Stop use and ask a doctor if new symptoms appear redness or swelling is present pain gets worse or lasts for more than 10 days fever gets worse or lasts for more than 3 days If pregnant or breast-feeding ask a health professional before use Keep out of reach of children Keep out of reach of children In case of overdose get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symtoms."],"when_using":["When using this product you may get drowsy avoid alcoholic drinks excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery limit the use of caffeine-containing medications, foods or beverages because too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally rapid heartbeat. The recommended dose of this product contains aboout as much caffeine as a cup of coffee."]}