{"active_ingredient":["Active ingredient Stannous Fluoride 0.454% w/w (0.15% fluoride ion)"],"dosage_and_administration":["Directions Adults and children 12 years of age and older: Apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least one minute, preferably after each meal or at least twice a day (morning and evening) or as directed by a dentist or physician. Make sure to brush all sensitive areas of the teeth. Do not swallow Children under 12 years of age: consult a dentist or doctor"],"effective_time":"20251112","id":"436ba302-220c-1f0e-e063-6294a90a11ac","inactive_ingredient":["Inactive ingredients glycerin, water, hydrated silica, pentasodium triphosphate, flavor, cocamidopropyl betaine, sodium lauryl sulfate, titanium dioxide, cellulose gum, sodium saccharin"],"indications_and_usage":["Uses aids in the prevention of dental cavities builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets or contact"],"keep_out_of_reach_of_children":["Keep out of reach of children. If more than used for brushing is accidentally swallowed get medical help or contact a poison control center right away."],"openfda":{"application_number":["M021"],"brand_name":["Care One Restore and Defend Sensitive Whitening"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Foodhold U.S.A."],"package_ndc":["41520-722-19"],"product_ndc":["41520-722"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["436ba302-220c-1f0e-e063-6294a90a11ac"],"spl_set_id":["81a380eb-8605-b280-e053-2a91aa0abd4b"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"]},"package_label_principal_display_panel":["CareOne® RESTORE & DEFEND SENSITIVE TOOTHPASTE FOR SENSITIVE TEETH & CAVITY PROTECTION DAILY PROTECTION FOR SENSITIVE TEETH WHITENING FRESH MINT NET WT 3.4 OZ (96.3 g) CareOne_RestoreDefend_Carton_2821293R1"],"purpose":["Purpose Anticavity/Antihypersensitivity"],"questions":["Questions or Comments? CALL 1-877-846-9949"],"set_id":"81a380eb-8605-b280-e053-2a91aa0abd4b","spl_product_data_elements":["Care One Restore and Defend Sensitive Whitening Stannous fluoride GLYCERIN SACCHARIN SODIUM WATER TITANIUM DIOXIDE SODIUM TRIPOLYPHOSPHATE ANHYDROUS CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM COCAMIDOPROPYL BETAINE SODIUM LAURYL SULFATE HYDRATED SILICA STANNOUS FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTRIBUTED BY: FOODHOLD U.S.A., LLC LANDOVER, MD 20785 For product questions or concerns, contact us at 1-877-849-9949"],"stop_use":["Stop use and ask a dentist if: the problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care by a dentist. pain/sensitivity still persists after 4 weeks of use"],"storage_and_handling":["Other information products containing stannous fluoride may produce surface staining of the teeth. Adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist. This product is specifically formulated to help prevent staining. store below 30°C (86°F)"],"version":"7","warnings":["Warnings When using this product, if irritation occurs discontinue use. Stop use and ask a dentist if: the problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care by a dentist. pain/sensitivity still persists after 4 weeks of use Keep out of reach of children. If more than used for brushing is accidentally swallowed get medical help or contact a poison control center right away."],"when_using":["When using this product, if irritation occurs discontinue use."]}