{"active_ingredient":["Benzalkonium chloride 0.13% Benzocaine 20% Menthol 0.26% Zinc chloride 0.15%"],"do_not_use":["do not use this product if you have a history of allergy to local anesthetics such as procaine, butacaine, benzocaine or other \"caine\" anesthetics"],"dosage_and_administration":["cut open tip of tube on score mark adults and children 2 years of age and older: apply to affected area up to 4 times daily or as directed by a dentist or doctor children between 2 and 12 years of age : ask a doctor before use. Should be supervised in the use of this product. children under 2 years of age: do not use Do not use: more than directed for more than 7 days unless told do so by a dentist or doctor for teething in children under 2 years of age"],"effective_time":"20251121","id":"441ef5c1-674c-f57e-e063-6394a90ab336","inactive_ingredient":["ammonium glycyrrhizate, chamomile, flavor, mineral oil, PEG-8, PEG-75, sodium saccharin, sorbic acid, titanium dioxide"],"indications_and_usage":["for temporary relief of pain due to toothaches to help protect against infection of minor oral irritation"],"keep_out_of_reach_of_children":["keep out of reach of children. In case of overdose or allergic reaction, get medical help or contact a Posion Control Center right away."],"openfda":{"application_number":["M017"],"brand_name":["Nighttime 4X Medicated Cream"],"generic_name":["BENZOCAINE"],"is_original_packager":[true],"manufacturer_name":["Rite Aid"],"nui":["N0000185508","N0000175629","N0000184306","M0000728"],"package_ndc":["11822-6300-1"],"pharm_class_cs":["Allergens [CS]"],"pharm_class_epc":["Standardized Chemical Allergen [EPC]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]"],"product_ndc":["11822-6300"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["2370903"],"spl_id":["441ef5c1-674c-f57e-e063-6394a90ab336"],"spl_set_id":["21645ed1-2dc0-223a-e063-6394a90ab021"],"substance_name":["BENZALKONIUM CHLORIDE","BENZOCAINE","ZINC CHLORIDE","MENTHOL"],"unii":["F5UM2KM3W7","U3RSY48JW5","86Q357L16B","L7T10EIP3A"],"upc":["0011822020138"]},"package_label_principal_display_panel":["2821632R1 RA Nigthtime toothache and Gum"],"purpose":["oral antiseptic oral pain reliever oral astringent"],"set_id":"21645ed1-2dc0-223a-e063-6394a90ab021","spl_product_data_elements":["Nighttime 4X Medicated Cream Benzocaine TITANIUM DIOXIDE POLYETHYLENE GLYCOL 400 CHAMOMILE BENZALKONIUM CHLORIDE BENZALKONIUM BENZOCAINE BENZOCAINE ZINC CHLORIDE ZINC CATION SORBIC ACID SACCHARIN SODIUM AMMONIUM GLYCYRRHIZATE MENTHOL MENTHOL POLYETHYLENE GLYCOL 3350 Cloudy white to yellow"],"stop_use":["Stop use and ask a doctor if swelling, rash or fever develops irritation, pain or redness persists or worsens symptoms do not improve in 7 days allergic reaction occurs"],"version":"3","warnings":["Methemoglobinemia warning: use of this product may cause methemoglobinemia, a serious condition that must be treated promptly because it reduces the amount of oxygen carried in blood. This can occur even if you have used this produt before. Stop use and seek immediate medical attention if you or a child in your care develops: pale, gray, or blue colored skin (cyanosis) headache rapid heart rate shortness of breath dizziness or lightheadedness fatigue or lack of energy Allergy alert: do not use this product if you have a history of allergy to local anesthetics such as procaine, butacaine, benzocaine or other caine anesthetics."]}