{"active_ingredient":["Active ingredient Pyrithione zinc 1%"],"dosage_and_administration":["Directions for best results use at least twice a week or as directed by a doctor. for maximum dandruff control, use every time you shampoo. shake before use. wet hair, massage onto scalp, rinse, repeat if desired."],"effective_time":"20251124","id":"445dba8b-a265-ddc5-e063-6394a90ac2b5","inactive_ingredient":["Inactive Ingredients Water, laura midopropyl betaine, sodium cocoyl isethionate, sodium lauroyl sarcosinate, sodium citrate, fragrance, sodium chloride, simmondsia chinensis (jojoba) seed oil, argania spinosa kernel oil, acrylates copolymer, polyquaternium-10, dimethiconol, tea-dodecylbenzenesulfonate, sodium benzoate, citric acid, sodium salicylate, laureth-23"],"indications_and_usage":["Uses helps prevent recurrence of flaking and itching associated with dandruff."],"keep_out_of_reach_of_children":["Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M032"],"brand_name":["Head and Shoulders Supreme Nourish and Smooth"],"generic_name":["PYRITHIONE ZINC"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-344-35","69423-344-90"],"product_ndc":["69423-344"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["209884","1043244"],"spl_id":["445dba8b-a265-ddc5-e063-6394a90ac2b5"],"spl_set_id":["8696c9d6-2306-4eb7-e053-2991aa0abd54"],"substance_name":["PYRITHIONE ZINC"],"unii":["R953O2RHZ5"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 350 mL Bottle Label head & shoulders ® PYRITHIONE ZINC DANDRUFF SCALP & HAIR SHAMPOO SUPREME NOURISH & SMOOTH WITH ARGAN OIL & JOJOBA OIL FREE FROM SULFATES PHOSPHATES PARABENS PHTHALATES DYES 11.8 FL OZ (350 mL) HS"],"purpose":["Purpose Anti-dandruff"],"questions":["Questions (or comments)? 1-800-723-9569"],"set_id":"8696c9d6-2306-4eb7-e053-2991aa0abd54","spl_product_data_elements":["Head and Shoulders Supreme Nourish and Smooth Pyrithione Zinc TRIETHANOLAMINE DODECYLBENZENESULFONATE LAURETH-23 ARGAN OIL POLYQUATERNIUM-10 (30000 MPA.S AT 2%) SODIUM BENZOATE WATER PYRITHIONE ZINC PYRITHIONE ZINC SODIUM CHLORIDE LAURAMIDOPROPYL BETAINE CITRIC ACID MONOHYDRATE JOJOBA OIL DIMETHICONOL (50000 CST) SODIUM COCOYL ISETHIONATE SODIUM SALICYLATE SODIUM CITRATE SODIUM LAUROYL SARCOSINATE"],"spl_unclassified_section":["Drug Facts","Dist. by PROCTER & GAMBLE, CINCINNATI, OH 45202"],"stop_use":["Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed."],"version":"8","warnings":["Warnings For external use only. When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed. Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water."]}