{"active_ingredient":["Active ingredients and purpose Active ingredients (in each capsule) Purposes Acetaminophen 325 mg…………….……….Pain reliever/fever reducer Dextromethorphan hydrobromide 10 mg…………..Cough suppressant Guaifenesin 200 mg…………………………………………..Expectorant Phenylephrine hydrochloride 5 mg………………...Nasal decongestant","Active ingredients and purpose Active ingredients (in each capsule) Purposes Acetaminophen 325 mg…………….… ……...Pain reliever/fever reducer Dextromethorphan hydrobromide 10 mg…… ………Cough suppressant Doxylamine succinate 6.25 mg…………… ………………...Antihistamine Phenylephrine hydrochloride 5 mg.....…… ………...Nasal decongestant"],"ask_doctor":["Ask a doctor before use if you have Ask a doctor before use if you have ● liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema ● cough with excessive phlegm (mucus)","Ask a doctor before use if you have Ask a doctor before use if you have ● liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● glaucoma ● cough with excessive phlegm (mucus) ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema","Ask a doctor or pharmacist before use if you are Ask a doctor or pharmacist before use if you are ● taking the blood thinning drug warfarin ● taking sedatives or tranquilizers"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin"],"do_not_use":["Do not use Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age","Do not use Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions Directions · do not take more than the recommended dose · do not take the Day and Night products at the same time; wait 4 hours after the last Night dose before starting Day product · adults and children 12 years and over: take 2 capsules with water every 4 hours. Do not exceed 6 capsules in 12 hours or as directed by a doctor. · children under 12 years: do not use","Directions Directions · do not take more than the recommended dose · do not take the Day and Night products at the same time; wait 4 hours after the last Day dose before starting Night product · adults and children 12 years and over: take 2 capsules with water every 4 hours. Do not exceed 4 capsules in 12 hours or as directed by a doctor. · children under 12 years: do not use"],"effective_time":"20251204","id":"4523aa8a-0db4-5337-e063-6394a90a8bda","inactive_ingredient":["Inactive ingredients Inactive ingredients FD&C red No. 40, gelatin, glycerin, lecithin, medium chain triglycerides, polyethylene glycol, potassium aluminum silicate, povidone, propylene glycol, purified water, shellac, sodium hydroxide, sorbitol sorbitan solution, titanium dioxide","Inactive ingredients Inactive ingredients D&C yellow No. 10, FD&C blue No. 1, gelatin, glycerin, polyethylene glycol, potassium aluminum silicate, povidone, propylene glycol, purified water, shellac, sodium hydroxide, sorbitol sorbitan solution, titanium dioxide"],"indications_and_usage":["Uses Uses · helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive · temporarily relieves these symptoms due to a cold or flu: · nasal congestion · sinus congestion and pressure · minor aches and pains · headache · cough · sore throat · temporarily reduces fever","Uses Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · nasal and sinus congestion · cough · sore throat · runny nose · sneezing · temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.","Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{"application_number":["M012"],"brand_name":["Alka-Seltzer Plus Cough, Mucus and Congestion Day and Night Powermax"],"generic_name":["ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"package_ndc":["0280-0035-01"],"product_ndc":["0280-0035"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1297288","1656815","2634364"],"spl_id":["4523aa8a-0db4-5337-e063-6394a90a8bda"],"spl_set_id":["a68df74d-dd26-3ae9-e053-2995a90a08d6"],"upc":["0016500584223"]},"other_safety_information":["Other information Other information · store at 15°- 25°C (59° - 77°F)","Other information Other information · store at 15° - 25°C (59° - 77°F)"],"package_label_principal_display_panel":["Product carton label 24 count PDP"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use.","If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purpose"],"questions":["Questions or comments Questions or comments? 1-800-986-0369 (Mon-Fri 9AM - 5PM EST)","Questions or comments Questions or comments? 1-800-986-0369 (Mon-Fri 9AM - 5PM EST)"],"set_id":"a68df74d-dd26-3ae9-e053-2995a90a08d6","spl_product_data_elements":["Alka-Seltzer Plus Cough, Mucus and Congestion Day and Night Powermax acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, guaifenesin, phenylephrine hydrochloride Alka-Seltzer Plus Maximum Strength Cough, Mucus and Congestion Day Powermax acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride SODIUM HYDROXIDE TITANIUM DIOXIDE ACETAMINOPHEN ACETAMINOPHEN DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE LECITHIN, SOYBEAN MEDIUM-CHAIN TRIGLYCERIDES POLYETHYLENE GLYCOL, UNSPECIFIED POVIDONE PROPYLENE GLYCOL WATER SORBITOL POTASSIUM ALUMINUM DISILICATE GUAIFENESIN GUAIFENESIN FD&C RED NO. 40 GELATIN SHELLAC SORBITAN elliptical ASP;S Alka-Seltzer Plus Maximum Strength Cough, Mucus and Congestion Night Powermax acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride ACETAMINOPHEN ACETAMINOPHEN SODIUM HYDROXIDE DOXYLAMINE SUCCINATE DOXYLAMINE PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE GLYCERIN GELATIN TITANIUM DIOXIDE SORBITAN POVIDONE DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN D&C YELLOW NO. 10 FD&C BLUE NO. 1 SHELLAC PROPYLENE GLYCOL POTASSIUM ALUMINUM DISILICATE POLYETHYLENE GLYCOL, UNSPECIFIED WATER SORBITOL ASP;N elliptical"],"spl_unclassified_section":["Drug Facts","Product name Do not take these products at the same time. Alka-Seltzer Plus® Maximum Strength Cough, Mucus & Congestion Day PowerMax® Gels","Product name Alka-Seltzer Plus® Maximum Strength Cough, Mucus & Congestion Night PowerMax® Gels"],"stop_use":["Stop use and ask a doctor if Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with fever, rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs","Stop use and ask a doctor if Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs"],"version":"5","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age Ask a doctor before use if you have Ask a doctor before use if you have ● liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema ● cough with excessive phlegm (mucus) Ask a doctor or pharmacist before use if you are Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin When using this product When using this product do not exceed recommended dosage Stop use and ask a doctor if Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with fever, rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.","Warnings Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children. Do not use Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age Ask a doctor before use if you have Ask a doctor before use if you have ● liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● glaucoma ● cough with excessive phlegm (mucus) ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema Ask a doctor or pharmacist before use if you are Ask a doctor or pharmacist before use if you are ● taking the blood thinning drug warfarin ● taking sedatives or tranquilizers When using this product When using this product ● do not exceed recommended dosage ● may cause marked drowsiness ● avoid alcoholic drinks ● alcohol, sedatives, and tranquilizers may increase drowsiness ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children Stop use and ask a doctor if Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"when_using":["When using this product When using this product do not exceed recommended dosage","When using this product When using this product ● do not exceed recommended dosage ● may cause marked drowsiness ● avoid alcoholic drinks ● alcohol, sedatives, and tranquilizers may increase drowsiness ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children"]}