{"active_ingredient":["Active ingredients (in each tablet) Purposes Aspirin 325 mg (NSAID)*…….………………………..Pain reliever/fever reducer Dextromethorphan hydrobromide 10 mg……………………Cough suppressant Phenylephrine bitartrate 7.8 mg.......……....…....…………..Nasal decongestant *nonsteroidal anti-inflammatory drug","Active ingredients (in each tablet) Purposes Aspirin 325 mg (NSAID)*…….…………………..Pain reliever/fever reducer Dextromethorphan hydrobromide 10 mg……..…..……Cough suppressant Doxylamine succinate 6.25 mg………………..…..………...…Antihistamine Phenylephrine bitartrate 7.8 mg.......…………..…...….Nasal decongestant *nonsteroidal anti-inflammatory drug"],"ask_doctor":["Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma •thyroid •disease diabetes cough that occurs with excessive phlegm (mucus) difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma, or emphysema a sodium-restricted diet","Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma diabetes thyroid disease glaucoma cough that occurs with excessive phlegm (mucus) a breathing problem such as emphysema or chronic bronchitis difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma,or emphysema a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis","Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis taking sedatives or tranquilizers"],"do_not_use":["Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of itsingredients ● in children under 12 years of age","Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients in children under 12 years of age"],"dosage_and_administration":["Directions do not take more than the recommended dose do not take the Day and Night products at the same time; wait 4 hours after taking the last Night dose before taking the Day product adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 4 tablets in 12 hours or as directed by a doctor. children under 12 years: do not use","Directions do not take more than the recommended dose do not take the Day and Night products at the same time; wait 4 hours after taking the last Day dose before taking the Night product adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 4 tablets in 12 hours or as directed by a doctor. children under 12 years: do not use"],"effective_time":"20251204","id":"45264ea9-aed7-8b75-e063-6394a90a74c1","inactive_ingredient":["Inactive ingredients anhydrous citric acid, calcium silicate, dimethicone, FD&C red #40, FD&C yellow #6, flavor, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose","Inactive ingredients anhydrous citric acid, calcium silicate, dimethicone, flavors, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose"],"indications_and_usage":["Uses temporarily relieves these symptoms due to a cold with cough: minor aches and pains headache sinus congestion and pressure cough sore throat nasal congestion temporarily reduces fever","Uses temporarily relieves these symptoms due to a cold: minor aches and pains headache runny nose sinus congestion and pressure cough sneezing sore throat nasal congestion temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away.","Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M012"],"brand_name":["Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night"],"generic_name":["ASPIRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"package_ndc":["0280-0069-01"],"product_ndc":["0280-0069"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1536498","2565491","2565492"],"spl_id":["45264ea9-aed7-8b75-e063-6394a90a74c1"],"spl_set_id":["c2232241-6e57-1427-e053-2995a90a488a"],"upc":["0016500594604"]},"other_safety_information":["Other information each tablet contains : potassium 78 mg; sodium 356 mg store at room temperature. Avoid excessive heat.","Other information each tablet contains : potassium 78 mg; sodium 356 mg store at room temperature. Avoid excessive heat."],"package_label_principal_display_panel":["Alka-Seltzer Plus® SEVERE COLD DAY/CITRUS NIGHT LEMON POWERFAST FIZZ™ DAY NON-DROWSY ASPIRIN (NSAID) /Pain Reliever - Fever Reducer DEXTROMETHORPHAN HBr/Cough Suppressant PHENYLEPHRINE BITARTRATE/Nasal Decongestant Nasal Decongestant Headache + Body Ache Cough Sore Throat Sinus Pressure 12 EFFERVESCENT TABLETS NEW NIGHT DOSING DIRECTIONS NIGHT Aspirin (NSAID) /Pain Reliever-Fever Reducer Dextromethorphan HBr/Cough Suppressant Doxylamine Succinate/Antihistamine Phenylephrine Bitartrate/Nasal Decongestant Nasal congestion Headache + Body Ache Cough Runny Nose Sore Throat 8 EFFERVESCENT TABLETS Carton 20 count"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding , ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.","If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":["",""],"questions":["Questions or comments? 1-800-986-0369 (Mon – Fri 9AM – 5PM EST)","Questions or comments? 1-800-986-0369 (Mon- Fri 9AM – 5PM EST)"],"set_id":"c2232241-6e57-1427-e053-2995a90a488a","spl_product_data_elements":["Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night aspirin, dextromethorphan hydrobromide, phenylephrine bitartrate Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy asprin, dextromethorphan hydrobromide, phenylephrine bitartrate MANNITOL POTASSIUM BICARBONATE POVIDONE SODIUM BICARBONATE ASPIRIN ASPIRIN DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN PHENYLEPHRINE BITARTRATE PHENYLEPHRINE CALCIUM SILICATE FD&C RED NO. 40 FD&C YELLOW NO. 6 SUCRALOSE ANHYDROUS CITRIC ACID DIMETHICONE ASP Alka-Seltzer Plus Severe Cold Night PowerFast Fizz aspirin, doxylamine succinate, dextromethorphan hydrobromide, phenylephrine bitartrate DOXYLAMINE SUCCINATE DOXYLAMINE DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN SUCRALOSE SODIUM BICARBONATE ASPIRIN ASPIRIN PHENYLEPHRINE BITARTRATE PHENYLEPHRINE POTASSIUM BICARBONATE MANNITOL POVIDONE DIMETHICONE CALCIUM SILICATE ANHYDROUS CITRIC ACID ASP;NT"],"spl_unclassified_section":["Drug Facts Alka-Seltzer Plus® Severe Cold PowerFast Fizz Day Effervescent Tablets","Alka-Seltzer Plus® Cold PowerFast Fizz Night Effervescent Tablets"],"stop_use":["Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding feel faint vomit blood have bloody or black stools have stomach pain that does not get better pain, cough, or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur ringing in the ears or loss of hearing occurs cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. nervousness, dizziness, or sleeplessness occurs","Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding feel faint vomit blood have bloody or black stools have stomach pain that does not get better pain, cough, or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur ringing in the ears or loss of hearing occurs cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. nervousness, dizziness, or sleeplessness occurs"],"version":"5","warnings":["Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include: · hives · facial swelling · asthma (wheezing) · shock Stomach bleeding warning : This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you ● are age 60 or older ● have had stomach ulcers or bleeding problems ● take a blood thinning (anticoagulant) or steroid drug ● take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ● have 3 or more alcoholic drinks every day while using this product ● take more or for a longer time than directed Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of itsingredients ● in children under 12 years of age Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma •thyroid •disease diabetes cough that occurs with excessive phlegm (mucus) difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma, or emphysema a sodium-restricted diet Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis When using this product do not exceed recommended dosage. Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding feel faint vomit blood have bloody or black stools have stomach pain that does not get better pain, cough, or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur ringing in the ears or loss of hearing occurs cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. nervousness, dizziness, or sleeplessness occurs If pregnant or breast-feeding , ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away.","Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert : Aspirin may cause a severe allergic reaction which may include: hives facial swelling · asthma (wheezing) shock Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you are age 60 or older have had stomach ulcers or bleeding problems artake a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directed Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children. Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients in children under 12 years of age Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma diabetes thyroid disease glaucoma cough that occurs with excessive phlegm (mucus) a breathing problem such as emphysema or chronic bronchitis difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma,or emphysema a sodium-restricted diet Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis taking sedatives or tranquilizers When using this product do not exceed recommended dosage may cause marked drowsiness avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding feel faint vomit blood have bloody or black stools have stomach pain that does not get better pain, cough, or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur ringing in the ears or loss of hearing occurs cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. nervousness, dizziness, or sleeplessness occurs If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product do not exceed recommended dosage.","When using this product do not exceed recommended dosage may cause marked drowsiness avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children"]}