{"active_ingredient":["Active ingredients (in each tablet) Acetaminophen 325 mg…………….……….Pain reliever/fever reducer Dextromethorphan hydrobromide 10 mg…………..Cough suppressant Phenylephrine hydrochloride 5 mg…………………Nasal decongestant"],"ask_doctor":["Ask a doctor before use if liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● cough that occurs with excessive phlegm (mucus) ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin"],"do_not_use":["Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions Directions do not take more than the recommended dose · do not take the Day and Night products at the same time; wait 4 hours after the last Night dose before starting Day product. · adults and children 12 years and over: take 2 capsules with water every 4 hours. Do not exceed 6 capsules in 12 hours or as directed by a doctor. · children under 12 years: do not use"],"effective_time":"20251204","id":"452656ff-79e2-0871-e063-6294a90ac49d","inactive_ingredient":["FD&C yellow #6, ferric oxide, gelatin, glycerin, polyethylene glycol, potassium aluminum silicate, povidone, propylene glycol, purified water, shellac, sodium hydroxide, sorbitol sorbitan solution, titanium dioxide"],"indications_and_usage":["Uses temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · sore throat · nasal congestion · sinus congestion and pressure · temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M012"],"brand_name":["Alka-Seltzer Plus Cold Day and Night PowerMax gels"],"generic_name":["ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE, DOXYLAMINE SUCCINATE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"package_ndc":["0280-0099-01"],"product_ndc":["0280-0099"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1086997","1297288","2634363"],"spl_id":["452656ff-79e2-0871-e063-6294a90ac49d"],"spl_set_id":["f6c73f61-f4fc-377f-e053-6294a90a3797"],"upc":["0016500583462"]},"other_safety_information":["Other information ● store at room temperature. Avoid temperatures above 40ºC (104ºF)."],"package_label_principal_display_panel":["Package Display Label PDP"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding , ask a health professional before use."],"purpose":[""],"questions":["Questions or comments? 1-800-986-0369 (Mon-Fri 9AM -5PM EST)"],"set_id":"f6c73f61-f4fc-377f-e053-6294a90a3797","spl_product_data_elements":["Alka-Seltzer Plus Cold Day and Night PowerMax gels Acetaminophen, Dextromethorphan hydrobromide, Phenylephrine bitartrate, Doxylamine succinate Alka-Seltzer Plus Maximum Strength Sinus, Congestion and Pain Power Max Gels Acetaminophen, Dextromethorphan Hydrobromide , Phenylephrine Hydrochloride TITANIUM DIOXIDE POTASSIUM ALUMINUM DISILICATE PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE ACETAMINOPHEN ACETAMINOPHEN GLYCERIN WATER SORBITAN DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN SODIUM HYDROXIDE GELATIN POVIDONE POLYETHYLENE GLYCOL, UNSPECIFIED SORBITOL SHELLAC FD&C YELLOW NO. 6 ASP;CC Alka Seltzer Plus Maximum Strength Sinus, Allergy And Cough Power Max Gels Acetaminophen, Dextromethorphan hydrobromide , Doxylamine succinate, Phenylephrine hydrochloride SHELLAC DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN DOXYLAMINE SUCCINATE DOXYLAMINE ACETAMINOPHEN ACETAMINOPHEN PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE D&C YELLOW NO. 10 WATER POTASSIUM ALUMINUM DISILICATE SORBITAN SODIUM BENZOATE GLYCERIN Elliptical ASP;N"],"spl_unclassified_section":["Alka-Seltzer Plus® Maximum Strength Sinus Congestion & Pain Day PowerMax® Gels","Drug Facts","SPL"],"stop_use":["Stop use and ask a doctor if pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs"],"version":"11","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert : Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning : If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly."],"when_using":["When using this product do not exceed recommended dosage"]}