{"active_ingredient":["Active ingredients (in each tablet) Purposes Acetaminophen 162.5 mg………….………...Pain reliever/fever reducer Chlorpheniramine maleate 2 mg……………………..……..Antihistamine Dextromethorphan hydrobromide 5 mg…….………Cough suppressant"],"ask_doctor":["Ask a doctor before use if you have ● liver disease ● glaucoma ● cough with excessive phlegm (mucus) ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema ● a sodium restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are ● taking the blood thinning drug warfarin ● taking sedatives or tranquilizers"],"do_not_use":["Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions Directions · do not take more than the recommended dose · adults and children 12 years and over: take 2 tablets every 4 hours. Do not exceed 12 tablets in 24 hours or as directed by a doctor. · do not swallow tablets whole. Chew or crush tablets completely before swallowing. · children under 12 years: do not use"],"effective_time":"20251204","id":"45266217-c6ae-a64a-e063-6394a90a92cf","inactive_ingredient":["Inactive ingredients anhydrous citric acid, betadex, carboxymethylcellulose, colloidal silicon dioxide, ethylcellulose, flavors, magnesium searate, mannitol, microcrystalline cellulose, polyethylene, sodium bicarbonate, sodium carbonate, sodium starch glycolate, stearic acid, sucralose, xylitol"],"indications_and_usage":["Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · runny nose · sneezing · sore throat · temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms"],"openfda":{"application_number":["M012"],"brand_name":["Alka-Seltzer Plus Cold and Flu FizzyChews"],"generic_name":["CHLORPHENIRAMINE MALEATE, ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"package_ndc":["0280-0151-01","0280-0151-02"],"product_ndc":["0280-0151"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["2678231"],"spl_id":["45266217-c6ae-a64a-e063-6394a90a92cf"],"spl_set_id":["149330be-24bd-b4a4-e063-6394a90a9007"],"substance_name":["DEXTROMETHORPHAN HYDROBROMIDE","CHLORPHENIRAMINE MALEATE","ACETAMINOPHEN"],"unii":["9D2RTI9KYH","V1Q0O9OJ9Z","362O9ITL9D"],"upc":["0016500601692"]},"other_safety_information":["Other information ● each tablet contains: sodium 17 mg ● store at room temperature. Avoid excessive heat above 40 o C (104 o F)"],"package_label_principal_display_panel":["Alka-Seltzer® PLUS Orange Flavor Cold & Flu FIZZY CHEWS ACETAMINOPHEN/Pain Reliever-Fever Reducer Chlorpheniramine Maleate/Antihistamine Dextromethorphan HBr/ Cough Supressant Phenylephrine Hydrochloride/Nasal Decongestant Cough Runny Nose Sneezing Fever & Body Ache Sore Throat ACTIVATES WITHOUT WATER 24 CHEWABLE TABLETS ASP Cold and Flu FizzyChews"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding , ask a health professional before use."],"purpose":[""],"questions":["Questions or comments Questions or comments? 1-800-986-0369 (Mon-Fri 9AM - 5PM EST)"],"set_id":"149330be-24bd-b4a4-e063-6394a90a9007","spl_product_data_elements":["Alka-Seltzer Plus Cold and Flu FizzyChews chlorpheniramine maleate, acetaminophen, dextromethorphan hydrobromide SODIUM STARCH GLYCOLATE TYPE A XYLITOL ANHYDROUS CITRIC ACID STEARIC ACID DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN MAGNESIUM STEARATE CHLORPHENIRAMINE MALEATE CHLORPHENIRAMINE MANNITOL SUCRALOSE SILICON DIOXIDE SODIUM BICARBONATE ACETAMINOPHEN ACETAMINOPHEN BETADEX MICROCRYSTALLINE CELLULOSE 102 SCG ASP;11"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition."],"version":"2","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age Ask a doctor before use if you have ● liver disease ● glaucoma ● cough with excessive phlegm (mucus) ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema ● a sodium restricted diet Ask a doctor or pharmacist before use if you are ● taking the blood thinning drug warfarin ● taking sedatives or tranquilizers When using this product ● marked drowsiness may occur ● avoid alcoholic drinks ● excitability may occur, especially in children ● alcohol, sedatives, and tranquilizers may increase drowsiness ● be careful when driving a motor vehicle or operating machinery Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding , ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms"],"when_using":["When using this product ● marked drowsiness may occur ● avoid alcoholic drinks ● excitability may occur, especially in children ● alcohol, sedatives, and tranquilizers may increase drowsiness ● be careful when driving a motor vehicle or operating machinery"]}