{"active_ingredient":["Active ingredients (in each tablet) Purpose Anhydrous citric acid 1000 mg Antacid Aspirin 500 mg Analgesic Sodium bicarbonate (heat-treated) 1985 mg Antacid"],"active_ingredient_table":["
Active ingredients (in each tablet)Purpose
Anhydrous citric acid 1000 mgAntacid
Aspirin 500 mgAnalgesic
Sodium bicarbonate (heat-treated) 1985 mgAntacid
"],"ask_doctor":["Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma you have a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are presently taking a prescription drug. Antacids may interact with certain prescription drugs. taking a prescription drug for anticoagulation (blood thinning), diabetes, gout, or arthritis"],"do_not_use":["Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients"],"dosage_and_administration":["Directions fully dissolve 2 tablets in 4 ounces of water before taking adults and children 12 years and over 2 tablets every 6 hours, or as directed by a doctor do not exceed 7 tablets in 24 hours adults 60 years and over 2 tablets every 6 hours, or as directed by a doctor do not exceed 3 tablets in 24 hours children under 12 years consult a doctor"],"dosage_and_administration_table":["
adults and children 12 years and over2 tablets every 6 hours, or as directed by a doctordo not exceed 7 tablets in 24 hours
adults 60 years and over2 tablets every 6 hours, or as directed by a doctordo not exceed 3 tablets in 24 hours
children under 12 yearsconsult a doctor
"],"effective_time":"20251204","id":"45266611-610c-a481-e063-6394a90a1bf0","inactive_ingredient":["Inactive ingredients flavor"],"indications_and_usage":["Uses for the temporary relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains upset stomach with headache from overindulgence in food or drink headache, body aches, and pain alone"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M001"],"brand_name":["Alka-Seltzer Extra Strength"],"generic_name":["ANHYDROUS CITRIC ACID, SODIUM BICARBONATE, AND ASPIRIN"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"nui":["N0000175833","N0000175835","N0000175980","N0000008556","N0000175089","N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["0280-0211-24"],"pharm_class_cs":["Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Calculi Dissolution Agent [EPC]","Anti-coagulant [EPC]","Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Acidifying Activity [MoA]","Calcium Chelating Activity [MoA]","Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Decreased Coagulation Factor Activity [PE]","Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["0280-0211"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1872085","1872088"],"spl_id":["45266611-610c-a481-e063-6394a90a1bf0"],"spl_set_id":["49b73bd5-6465-05eb-e054-00144ff88e88"],"substance_name":["ANHYDROUS CITRIC ACID","SODIUM BICARBONATE","ASPIRIN"],"unii":["XF417D3PSL","8MDF5V39QO","R16CO5Y76E"],"upc":["0016500044048"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 24 Tablets Carton Alka- Seltzer ® ANTACID & PAIN RELIEF MEDICINE FAST RELIEF OF: Acid Indigestion Upset Stomach Heartburn with Headache Body Aches XTRA STRENGTH 24 EFFERVESCENT TABLETS ASES24"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":["Active ingredients (in each tablet) Purpose Anhydrous citric acid 1000 mg Antacid Aspirin 500 mg Analgesic Sodium bicarbonate (heat-treated) 1985 mg Antacid"],"purpose_table":["
Active ingredients (in each tablet)Purpose
Anhydrous citric acid 1000 mgAntacid
Aspirin 500 mgAnalgesic
Sodium bicarbonate (heat-treated) 1985 mgAntacid
"],"questions":["Questions or comments? 1-800-986-0369 (Mon - Fri 9AM - 5PM EST)"],"set_id":"49b73bd5-6465-05eb-e054-00144ff88e88","spl_product_data_elements":["Alka-Seltzer Extra Strength Anhydrous Citric Acid, Sodium Bicarbonate, and Aspirin LEMON ANHYDROUS CITRIC ACID ANHYDROUS CITRIC ACID SODIUM BICARBONATE SODIUM CATION ASPIRIN ASPIRIN White tablet ALKA;SELTZER;EX;S"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding • feel faint • vomit blood • have bloody or black stools • have stomach pain that does not get better symptoms get worse or last more than 10 days redness or swelling is present ringing in the ears or a loss of hearing occurs new symptoms occur"],"storage_and_handling":["Other information each tablet contains: sodium 588 mg store at room temperature. Avoid excessive heat. Alka-Seltzer Extra Strength in water contains principally the antacid sodium citrate and the analgesic sodium acetylsalicylate"],"version":"5","warnings":["Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include hives facial swelling asthma (wheezing) shock Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directed Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma you have a sodium-restricted diet Ask a doctor or pharmacist before use if you are presently taking a prescription drug. Antacids may interact with certain prescription drugs. taking a prescription drug for anticoagulation (blood thinning), diabetes, gout, or arthritis When using this product do not exceed recommended dosage Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding • feel faint • vomit blood • have bloody or black stools • have stomach pain that does not get better symptoms get worse or last more than 10 days redness or swelling is present ringing in the ears or a loss of hearing occurs new symptoms occur If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product do not exceed recommended dosage"]}