{"active_ingredient":["Active ingredients (in each capsule) Acetaminophen 325 mg Dextromethorphan hydrobromide 10 mg Phenylephrine hydrochloride 5 mg","Active ingredients (in each capsule) Acetaminophen 325 mg Dextromethorphan hydrobromide 10 mg Phenylephrine hydrochloride 5 mg"],"ask_doctor":["Ask a doctor before use if you have ● liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● cough with excessive phlegm (mucus) ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema","Ask a doctor before use if you have ● liver disease ● heart disease ● high blood pressure ● thyroid disease ● diabetes ● cough with excessive phlegm (mucus) ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin","Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin"],"do_not_use":["Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age","Do not use ● with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions Directions · do not take more than the recommended dose · adults and children 12 years and over: take 2 capsules with water every 4 hours. Do not exceed 10 capsules in 24 hours or as directed by a doctor. · children under 12 years: do not use","Directions · do not take more than the recommended dose · adults and children 12 years and over: take 2 capsules with water every 4 hours. Do not exceed 10 capsules in 24 hours or as directed by a doctor. · children under 12 years: do not use"],"effective_time":"20251204","id":"45267c79-03c6-b84d-e063-6394a90aa9eb","inactive_ingredient":["Inactive ingredients FD&C red #40, FD&C yellow #6, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, shellac, sodium hydroxide, sorbitol sorbitan solution, titanium dioxide","Inactive ingredients FD&C red #40, FD&C yellow #6, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, shellac, sodium hydroxide, sorbitol sorbitan solution, titanium dioxide"],"indications_and_usage":["Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · sore throat · nasal and sinus congestion · temporarily reduces fever","Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · sore throat · nasal and sinus congestion · temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.","Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"openfda":{"application_number":["M012"],"brand_name":["Alka-Seltzer Plus Maximum Strength Day and Night Cold and Flu"],"generic_name":["ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"package_ndc":["0280-1581-40"],"product_ndc":["0280-1581"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1086997","1297288","2634363"],"spl_id":["45267c79-03c6-b84d-e063-6394a90aa9eb"],"spl_set_id":["54236151-37db-0b5a-e054-00144ff88e88"],"upc":["0016500555889"]},"other_safety_information":["Other information Other information ● store at room temperature. Avoid excessive heat above 40°C (104°F).","Other information Other information ● store at room temperature. Avoid excessive heat above 40°C (104°F)."],"package_label_principal_display_panel":["Carton 40 count Alka-Seltzer PLUS MAXIMUM STRENGTH Cold & Flu Day NON-DROWSY ACETAMINOPHEN / Pain Reliever-Fever Reducer Dextromethorphan HBr / Cough Suppressant Phenylephrine HCl / Nasal Decongestant Nasal Congestion Headache & Body Ache Cough Sore Throat Sinus Pressure 24 LIQUID GELS (Liquid Filled Capsules) NIGHT ACETAMINOPHEN / Pain Reliever-Fever Reducer Dextromethorphan HBr / Cough Suppressant Doxylamine Succinate / Antihistamine Phenylephrine HCl / Nasal Decongestant Nasal Congestion Headache & Body Ache Cough Runny Nose Sore Throat 16 LIQUID GELS (Liquid Filled Capsules) Carton 40"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use.","If pregnant or breast-feeding , ask a health professional before use."],"purpose":["Purposes Pain reliever/fever reducer Cough suppressant Nasal decongestant","Purposes Pain reliever/fever reducer Cough suppressant Nasal decongestan"],"questions":["Questions or comments? 1-800-986-0369 (Mon-Fri 9AM -5PM EST)","Questions or comments? Questions or comments? 1-800-986-0369 (Mon-Fri 9AM -5PM EST)"],"set_id":"54236151-37db-0b5a-e054-00144ff88e88","spl_product_data_elements":["Alka-Seltzer Plus Maximum Strength Day and Night Cold and Flu Acetaminophen, Dextromethorphan hydrobromide, Doxylamine succinate, Phenylephrine hydrochloride Alka-Seltzer Plus Maximum Strength Night Cold and Flu Acetaminophen, Dextromethorphan hydrobromide, Doxylamine succinate, Phenylephrine hydrochloride DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN GELATIN GLYCERIN POLYETHYLENE GLYCOL, UNSPECIFIED PROPYLENE GLYCOL WATER POVIDONE SHELLAC SODIUM HYDROXIDE SORBITAN TITANIUM DIOXIDE SORBITOL FD&C BLUE NO. 1 D&C YELLOW NO. 10 DOXYLAMINE SUCCINATE DOXYLAMINE PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE ACETAMINOPHEN ACETAMINOPHEN AS;NITE Alka-Seltzer Plus Maximum Strength Day Cold and Flu Acetaminophen, Dextromethorphan hydrobromide, Phenylephrine hydrochloride TITANIUM DIOXIDE DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN PHENYLEPHRINE HYDROCHLORIDE PHENYLEPHRINE ACETAMINOPHEN ACETAMINOPHEN FD&C RED NO. 40 POLYETHYLENE GLYCOL, UNSPECIFIED FD&C YELLOW NO. 6 GLYCERIN GELATIN POVIDONE PROPYLENE GLYCOL WATER SHELLAC SODIUM HYDROXIDE SORBITOL SORBITAN AS;DC"],"spl_unclassified_section":["Alka-Seltzer Plus® Maximum Strength Day Cold & Flu Liquid Gels Alka-Seltzer Plus® Maximum Strength Day Cold & Flu Liquid Gels","Drug Facts","Alka-Seltzer Plus® Maximum Strength Night Cold & Flu Liquid Gels","Drug Facts"],"version":"9","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning : If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.","Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly."],"when_using":["When using this product do not exceed recommended dosage Stop use and ask a doctor if pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs","When using this product do not exceed recommended dosage Stop use and ask a doctor if · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs"]}