{"active_ingredient":["Active ingredient (in each tablet) Aspirin 650 mg (NSAID)* Caffeine 65 mg *nonsteroidal anti-inflammatory drug"],"dosage_and_administration":["Directions adults and children 12 years and over: take contents of 1 powder pack every 6 hours. Dissolve powder on tongue, followed by a full glass of water. Do not exceed 4 powder packs in 24 hours. ● children under 12 years: consult a doctor"],"effective_time":"20251205","id":"45372de8-2f8f-007c-e063-6294a90a4f7b","inactive_ingredient":["Inactive Ingredients anhydrous citric acid, flavors, mannitol, neotame, sodium citrate monobasic, sucralose"],"indications_and_usage":["Uses temporarily relieves minor aches and pains due to: • headache • muscle pain • backache • menstrual cramps • minor pain of arthritis • temporarily reduces feve"],"keep_out_of_reach_of_children":[""],"openfda":{"application_number":["M013"],"brand_name":["Bayer Rapid Relief"],"generic_name":["ASPIRIN/CAFFEINE ORAL POWDER"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"nui":["N0000175739","N0000175729","N0000175790","M0023046","N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["0280-0103-01","0280-0103-02","0280-0103-03"],"pharm_class_cs":["Xanthines [CS]","Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Central Nervous System Stimulant [EPC]","Methylxanthine [EPC]","Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Central Nervous System Stimulation [PE]","Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["0280-0103"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["2626726"],"spl_id":["45372de8-2f8f-007c-e063-6294a90a4f7b"],"spl_set_id":["f1fecbb0-5b55-fe8f-e053-2995a90a0977"],"substance_name":["CAFFEINE","ASPIRIN"],"unii":["3G6A5W338E","R16CO5Y76E"],"upc":["0312843597631"]},"package_label_principal_display_panel":["ASPIRIN_RapidReliefPowder"],"purpose":["Purpose Pain reliever/fever reducer Pain reliever aid"],"questions":["Questions or comments? 1-800-331-4536 (Mon-Fri 9AM - 5PMEST)"],"set_id":"f1fecbb0-5b55-fe8f-e053-2995a90a0977","spl_product_data_elements":["Bayer Rapid Relief Aspirin/Caffeine Oral Powder CAFFEINE CAFFEINE SUCRALOSE ANHYDROUS CITRIC ACID MANNITOL NEOTAME MONOSODIUM CITRATE ASPIRIN ASPIRIN"],"spl_unclassified_section":["Drug Facts"],"storage_and_handling":["Other information ● phenylketonurics: contains phenylalanine 0.0017 mg per powder pack ● save carton for full directions and warnings ● Store between 20°- 25 °C (68°-77° F)"],"version":"10","warnings":["Warnings Reye’s syndrome : Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert : Aspirin may cause a severe allergic reaction which may include: • hives • facial swelling • asthma (wheezing) • shock Stomach bleeding warning : This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you ● are age 60 or older ● have had stomach ulcers or bleeding problems ● take a blood thinning (anticoagulant) or steroid drug ● take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ● have 3 or more alcoholic drinks every day while using this product ● take more or for a longer time than directed Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you have ever had an allergic reaction to this product or any of its Ingredients Ask a doctor before use if ● stomach bleeding warning applies to you ● you have a history of stomach problems, such as heartburn ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ● you are taking a diuretic ● you have asthma Ask a doctor or pharmacist before use if you are taking a prescription drug for ● gout ● diabetes ● arthritis Stop use and ask a doctor if ● an allergic reaction occurs. Seek medical help right away. ● you experience any of the following signs of stomach bleeding: ● feel faint ● vomit blood ● have bloody or black stools ● have stomach pain that does not get better ● pain gets worse or lasts more than 10 days ● fever gets worse or lasts more than 3 days ● redness or swelling is present ● new symptoms occur ● ringing in the ears or a loss of hearing occurs If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away."]}