{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20251211","id":"45b38bbb-f547-c3f3-e063-6394a90aed42","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, cellulose gum, sodium saccharin, carbomer, polysorbate 80, mica, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 204 g Tube Carton Crest plus ANTICAVITY FLUORIDE TOOTHPASTE NET WT 5.4 OZ (153 g) ACTIVE FOAM EXTRA WHITENING WITH TARTAR PROTECTION A WHITER SMILE IN ONE TUBE clean mint Label"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"151d74c3-cd42-9f31-e063-6294a90a3d62","spl_product_data_elements":["Crest Plus Extra Whitening Sodium Fluoride TITANIUM DIOXIDE FD&C BLUE NO. 1 POLYSORBATE 80 WATER SORBITOL HYDRATED SILICA MICA CARBOXYPOLYMETHYLENE SODIUM ACID PYROPHOSPHATE SODIUM LAURYL SULFATE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM SODIUM HYDROXIDE SACCHARIN SODIUM SODIUM FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"4","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}