{"active_ingredient":["Active ingredient Pyrithione zinc 0.5%"],"dosage_and_administration":["Directions for best results use at least twice a week or as directed by a doctor. apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well."],"effective_time":"20251218","id":"4640c427-fbac-1ff7-e063-6394a90a4e63","inactive_ingredient":["Inactive ingredients Water, stearyl alcohol, behentrimonium chloride, cetyl alcohol, argania spinosa kernel oil, zea mays (corn) silk extract, cocos nucifera (coconut) fruit extract, fragrance, phenoxyethanol, benzyl alcohol, methylchloroisothiazolinone, methylisothiazolinone"],"indications_and_usage":["Uses helps prevent recurrence of flaking and itching associated with dandruff."],"keep_out_of_reach_of_children":["Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M032"],"brand_name":["Head and Shoulders Supreme Detox and Hydrate Conditioner"],"generic_name":["PYRITHIONE ZINC"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-347-27"],"product_ndc":["69423-347"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["1043014","1044465"],"spl_id":["4640c427-fbac-1ff7-e063-6394a90a4e63"],"spl_set_id":["86ab72bc-4e9d-0075-e053-2a91aa0a1135"],"substance_name":["PYRITHIONE ZINC"],"unii":["R953O2RHZ5"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 247 mL Tube Label head & shoulders ® PYRITHION ZINC DANDRUFF SCALP & HAIR CONDITIONER SUPREME DETOX & HYDRATE WITH ARGAN OIL & COCONUT WATER FREE FROM SULFATES PARABENS PHTHALATES DYES 9.4 FL OZ (278 mL) HS"],"purpose":["Purpose Anti-dandruff"],"questions":["Questions (or comments)? 1-800-723-9569"],"set_id":"86ab72bc-4e9d-0075-e053-2a91aa0a1135","spl_product_data_elements":["Head and Shoulders Supreme Detox and Hydrate Conditioner Pyrithione Zinc BENZYL ALCOHOL COCONUT OIL METHYLCHLOROISOTHIAZOLINONE METHYLISOTHIAZOLINONE PYRITHIONE ZINC PYRITHIONE ZINC ARGAN OIL CORN SILK BEHENTRIMONIUM CHLORIDE WATER STEARYL ALCOHOL CETYL ALCOHOL PHENOXYETHANOL"],"spl_unclassified_section":["Drug Facts","Dist. by PROCTER & GAMBLE, CINCINNATI, OH 45202"],"stop_use":["Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed."],"version":"8","warnings":["Warnings For external use only. When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed. Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water."]}