{"active_ingredient":["Active ingredient Pyrithione zinc .75%"],"dosage_and_administration":["Directions for best results use at least twice a week or as directed by a doctor. apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well. for maximum dandruff control, use every time you shampoo."],"effective_time":"20251218","id":"46417fb5-59f1-15d4-e063-6394a90a10b2","inactive_ingredient":["Inactive ingredients Water, stearyl alcohol, cetyl alcohol, stearamidopropyl dimethylamine, glutamic acid, dimethicone, fragrance, phenoxyethanol, benzyl alcohol, sodium chloride, citric acid, honey extract,methylchloroisothiazolinone, methylisothiazolinone."],"indications_and_usage":["Uses helps prevent recurrence of flaking and itching associated with dandruff."],"keep_out_of_reach_of_children":["Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M032"],"brand_name":["Head and Shoulders Clinical Dandruff Defense Dry Scalp Rescue"],"generic_name":["PYRITHIONE ZINC"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-568-27"],"product_ndc":["69423-568"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["1441558","1441563"],"spl_id":["46417fb5-59f1-15d4-e063-6394a90a10b2"],"spl_set_id":["c7bc3942-6943-2ea5-e053-2a95a90a42a9"],"substance_name":["PYRITHIONE ZINC"],"unii":["R953O2RHZ5"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - TUBE LABEL head & shoulders ® pyrithione zinc dandruff conditioner Clinical Dandruff Defense Dry Scalp Rescue with Manuka Honey 100% DANDRUFF PROTECTION SATISFACTION GUARANTEED* 9.1 FL OZ (270 mL) HS"],"purpose":["Purpose Anti-dandruff"],"questions":["Questions (or comments)? 1-800-723-9569"],"set_id":"c7bc3942-6943-2ea5-e053-2a95a90a42a9","spl_product_data_elements":["Head and Shoulders Clinical Dandruff Defense Dry Scalp Rescue Pyrithione Zinc METHYLCHLOROISOTHIAZOLINONE METHYLISOTHIAZOLINONE PYRITHIONE ZINC PYRITHIONE ZINC STEARAMIDOPROPYL DIMETHYLAMINE GLUTAMIC ACID PHENOXYETHANOL BENZYL ALCOHOL CITRIC ACID MONOHYDRATE HONEY SODIUM CHLORIDE STEARYL ALCOHOL CETYL ALCOHOL WATER DIMETHICONE"],"spl_unclassified_section":["Drug Facts","Dist. by PROCTER & GAMBLE, CINCINNATI, OH 45202"],"stop_use":["Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed."],"version":"4","warnings":["Warnings For external use only. When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed. Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water."]}