{"active_ingredient":["Active ingredient Pyrithione zinc 1%"],"dosage_and_administration":["Directions for best results use at least twice a week or as directed by a doctor. for maximum dandruff control, use every time you shampoo. shake before use. wet hair, massage onto scalp, rinse, repeat if desired."],"effective_time":"20251218","id":"464237ba-5eb7-e7c5-e063-6394a90a965e","inactive_ingredient":["Inactive ingredients Water, sodium lauryl sulfate, sodium laureth sulfate, glycol distearate, sodium chloride, zinc carbonate, cocamidopropyl betaine, sodium xylenesulfonate, fragrance, dimethicone, sodium benzoate, guar hydroxypropyltrimonium chloride, magnesium carbonate hydroxide, tocopheryl acetate, methylchloroisothiazolinone, methylisothiazolinone, blue 1, red 33"],"indications_and_usage":["Uses helps prevent recurrence of flaking and itching associated with dandruff."],"keep_out_of_reach_of_children":["Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M032"],"brand_name":["Head and Shoulders Classic Clean with Vitamin E"],"generic_name":["PYRITHIONE ZINC"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-647-11"],"product_ndc":["69423-647"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["209884","1043244"],"spl_id":["464237ba-5eb7-e7c5-e063-6394a90a965e"],"spl_set_id":["ecfde5bc-6100-d00c-e053-2995a90ac5dc"],"substance_name":["PYRITHIONE ZINC"],"unii":["R953O2RHZ5"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 1150 mL Bottle Label head & shoulders ® pyrithione zinc dandruff shampoo CLASSIC CLEAN SHAMPOO WITH VITAMIN E 38.8 FL OZ (1.15L) HS"],"purpose":["Purpose Anti-dandruff"],"questions":["Questions (or comments)? 1-800-723-9569"],"set_id":"ecfde5bc-6100-d00c-e053-2995a90ac5dc","spl_product_data_elements":["Head and Shoulders Classic Clean with Vitamin E Pyrithione Zinc ALPHA-TOCOPHEROL ACETATE FD&C BLUE NO. 1 D&C RED NO. 33 SODIUM LAURYL SULFATE GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE) WATER SODIUM LAURETH SULFATE DIMETHICONE ZINC CARBONATE GLYCOL DISTEARATE SODIUM XYLENESULFONATE COCAMIDOPROPYL BETAINE SODIUM CHLORIDE SODIUM BENZOATE MAGNESIUM CARBONATE HYDROXIDE METHYLCHLOROISOTHIAZOLINONE METHYLISOTHIAZOLINONE PYRITHIONE ZINC PYRITHIONE ZINC"],"spl_unclassified_section":["Drug Facts","MADE IN U.S.A. of U.S. and/or Imported Ingredients Dist. by PROCTER & GAMBLE, CINCINNATI, OH 45202"],"stop_use":["Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed."],"version":"4","warnings":["Warnings For external use only. When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed. Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water."]}