{"accessories":["Accessories"],"active_ingredient":["Active ingredient Stannous fluoride 0.454% w/w (0.13% w/v fluoride ion)"],"dosage_and_administration":["For adults and children 12 years of age or older, apply a small, pea-size amount of MI Paste ONE Perio to your toothbrush. For best results, brush for 2 minutes, expectorate and do not rinse; do not eat or drink for 30 minutes after brushing. Use twice daily. Replace cap after use. For children under 12 years of age, consult a dentist or physician."],"effective_time":"20251219","id":"4651cb98-dcfe-a45b-e063-6294a90ad8b2","inactive_ingredient":["Inactive ingredients Water, Glycerol, Silicon dioxide, RECALDENT® (CPP-ACP) Casein Phosphopeptide-Amorphous Calcium Phosphate, Sorbitol, CMC-Na, Propylene glycol, Sodium lauryl sulfate, Sodium citrate, Flavoring, Titanium dioxide, Xylitol, Sodium saccharin, Ethyl p-hydroxybenzoate, Propyl p-hydroxybenzoate, Butyl p-hydroxybenzoate"],"indications_and_usage":["Uses • Helps prevent gingivitis • Helps interfere with harmful effects of plaque associated with gingivitis • Aids in the prevention of cavities • Builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact"],"keep_out_of_reach_of_children":["• Keep out of reach of children"],"openfda":{"application_number":["M021"],"brand_name":["MIPaste One Perio"],"generic_name":["MIPASTE ONE PERIO"],"is_original_packager":[true],"manufacturer_name":["GC America Inc."],"package_ndc":["61596-300-40","61596-300-41","61596-300-10"],"product_ndc":["61596-300"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["4651cb98-dcfe-a45b-e063-6294a90ad8b2"],"spl_set_id":["d656b72d-48f8-4425-e053-2995a90ab1f2"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"]},"package_label_principal_display_panel":["Package Label"],"purpose":["Purposes Anti-gingivitis Anti-cavity Anti-sensitivity"],"set_id":"d656b72d-48f8-4425-e053-2995a90ab1f2","spl_product_data_elements":["MIPaste One Perio MIPaste One Perio WATER CALCIUM PHOSPHATE, UNSPECIFIED FORM CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED GLYCERIN SILICON DIOXIDE SACCHARIN SODIUM ETHYLPARABEN PROPYLENE GLYCOL SORBITOL SODIUM LAURYL SULFATE XYLITOL PROPYLPARABEN BUTYLPARABEN SODIUM CITRATE, UNSPECIFIED FORM TITANIUM DIOXIDE STANNOUS FLUORIDE FLUORIDE ION"],"version":"4","warnings":["• Keep out of reach of children • Stop use and ask a dentist if gingivitis, bleeding, or redness persists for more than 2 weeks, or if you have painful or swollen gums, pus from the gum line, loose teeth, or increasing spacing between the teeth. These may be signs of periodontitis, a serious form of gum disease. • When using this product for sensitivity, do not use longer than 4 weeks unless recommended by a dentist. • If more than the recommended amount of paste used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. Do not use on patients with a milk protein or hydroxybenzoates allergy. In case of allergic reaction, stop use, rinse mouth with water and seek medical advice."]}