{"active_ingredient":["Active Ingredients Drug Facts Active ingredients (in each 30 mL dose cup) Acetaminophen 650 mg Dextromethorphan HBr 30 mg Doxylamine Succinate 12.5 mg"],"ask_doctor":["Ask A Doctor Ask a doctor before use if you have a sodium restricted diet liver disease glaucoma cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema trouble urinating due to enlarged prostate gland"],"ask_doctor_or_pharmacist":["Ask A Doctor Or Pharmacist Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers if you are taking the blood thinning drug warfarin"],"do_not_use":["Do Not Use Do not use with any other drug containing acetaminophen (prescription or nonprescription) If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist If you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression,psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product to make a child sleepy"],"dosage_and_administration":["Directions Directions take only as recommended-see Overdose warnings Use dose cup or tablespoon (TBSP) do not exceed 4 doses per 24 hours adults and children 12 years and over 30 mL (2TBSP) every 6 hours children 4 to under 12 years ask a doctor children under 4 years do not use If taking Nite Time at night and Day Time during the day, limit total to 4 doses per 24 hours"],"effective_time":"20251226","id":"46e2c8b6-bd83-7100-e063-6294a90ac998","inactive_ingredient":["Inactive Ingredients Inactive ingredients: citric acid, D and C yellow No. 10, FD and C Green No. 3, FD and C Yellow No. 6, flavor, glycerin, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium citrate, sucrose"],"indications_and_usage":["Uses Uses temporarily relieves cold/flu symptoms: sore throat minor aches and pain runny nose and sneezing cough due to minor sore throat and bronchial irritation headache fever"],"keep_out_of_reach_of_children":["Keep Out Of Reach Of Children Keep out of reach of children."],"openfda":{"application_number":["M012"],"brand_name":["Nite-Time COLD/FLU Medicine"],"generic_name":["ACETAMINOPHEN"],"is_original_packager":[true],"manufacturer_name":["AptaPharma Inc."],"package_ndc":["76281-501-28","76281-501-25"],"product_ndc":["76281-501"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1043400"],"spl_id":["46e2c8b6-bd83-7100-e063-6294a90ac998"],"spl_set_id":["344440bc-d810-4296-93ec-e6ae6673856b"],"substance_name":["ACETAMINOPHEN","DEXTROMETHORPHAN HYDROBROMIDE","DOXYLAMINE SUCCINATE"],"unii":["362O9ITL9D","9D2RTI9KYH","V9BI9B5YI2"]},"other_safety_information":["Other Information Other information each 30 mL dose cup contains: sodium 45 mg store at room temperature"],"overdosage":["Overdose Warning Overdose warning: Taking more than the recommended dose can cause serious health problems. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"package_label_principal_display_panel":["Package Label - Night Time Cold & Flu Relief NDC 76281-501-28 AP SAFE *COMPARE TO the active ingredients in VICKS ® NYQUIL ® Night Time Acetaminophen – Pain Reliever/Fever Reducer Dextromethorphan HBr – Cough Suppressant Doxylamine Succinate – Antihistamine Multi-Symptom Cold & Flu Relief Original Flavor 12 FL OZ (354 mL) DO NOT USE IF IMPRINTED SHRINK BAND IS MISSING OR BROKEN Failure to follow these warnings could result in serious consequences *This product is not manufactured or distributed by Procter & Gamble, owner of the registered trademark Vicks® NyQuil®. Manufactured by: AptaPharma Inc., 1533 Union Ave., Pennsauken, NJ 08110 12 OZ 6 OZ res 501-28 12oz Botl 501-25 6 OZ"],"pregnancy_or_breast_feeding":["Pregnant Or Breast-Feeding If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purpose Purpose Pain reliever/fever reducer Cough suppressant Antihistamine"],"set_id":"344440bc-d810-4296-93ec-e6ae6673856b","spl_product_data_elements":["Nite-Time COLD/FLU Medicine ACETAMINOPHEN CITRIC ACID MONOHYDRATE D&C YELLOW NO. 10 FD&C GREEN NO. 3 FD&C YELLOW NO. 6 GLYCERIN POLYETHYLENE GLYCOL 400 PROPYLENE GLYCOL WATER SACCHARIN SODIUM SODIUM BENZOATE SODIUM CITRATE SUCROSE ACETAMINOPHEN ACETAMINOPHEN DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN DOXYLAMINE SUCCINATE DOXYLAMINE"],"stop_use":["Stop Use And Ask A Doctor Stop use and ask a doctor if redness or swelling is present symptoms do not get better within 7 days or are accompanied by a fever fever gets worse or lasts more than 3 days new symptoms occur cough lasts more than 7 days, comes back, or occurs with fever, rash, headache that lasts"],"version":"9","warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take ● more than 4 doses (30 mL each) in 24 hours, which is the maximum daily amount for this product ● with other drugs containing acetaminophen ● 3 or more alcoholic drinks everyday while using this product. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly."],"when_using":["When Using This Product When using this product do not use more than directed avoid alcoholic drinks excitability may occur, especially in children marked drowsiness may occur be careful when driving a motor vehicle or operating machinery alcohol, sedatives, and tranquilizers may increase drowsiness"]}