{"adverse_reactions":["ADVERSE REACTIONS Flushing, sweating, sharply lowered blood pressure, hypothermia, stupor and ultimately respiratory depression."],"contraindications":["CONTRAINDICATIONS Magnesium Chloride Injection should not be administered if there is renal impairment, marked myocardial disease or to comatose patients."],"description":["DESCRIPTION Magnesium Chloride Injection is a sterile solution of Magnesium Chloride Hexahydrate in Water for Injection q.s. Each mL contains Magnesium Chloride Hexahydrate 200 mg, Sodium Chloride 9 mg, Benzyl Alcohol 1% as a preservative, Water for Injection, q.s. pH adjusted with Hydrochloric Acid and/or Sodium Hydroxide. Total osmolarity equivalent to 2.951 mOsm/mL. Contains 1.97 mEq of Mg ++ and Cl - per mL. The structural formula is MgCl 2 •6H 2 O"],"dosage_and_administration":["DOSAGE AND ADMINISTRATION For intravenous infusion: 4 grams in 250 mL of 5% Dextrose Injection, at a rate not exceeding 3 mL per minute. Serum magnesium levels should serve as a guide to continued dosage."],"effective_time":"20211015","how_supplied":["HOW SUPPLIED Magnesium Chloride Injection 200 mg/mL (20% w/v). NDC 67457-134-50 50 mL Multiple-Dose Vial. Individually boxed. Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.] Manufactured for: Mylan Institutional LLC Morgantown, WV 26505 Manufactured by: Mylan Institutional Galway, Ireland 1084L101 Revised: 10/2021 MI:MAGNIJ:R4"],"id":"46f389a6-b16b-44af-b468-973805cc3c49","indications_and_usage":["INDICATIONS As an electrolyte replenisher in magnesium deficiencies."],"openfda":{"brand_name":["Magnesium Chloride"],"generic_name":["MAGNESIUM CHLORIDE"],"is_original_packager":[true],"manufacturer_name":["Mylan Institutional LLC"],"package_ndc":["67457-134-50"],"product_ndc":["67457-134"],"product_type":["HUMAN PRESCRIPTION DRUG"],"route":["INTRAVENOUS"],"rxcui":["311422"],"spl_id":["46f389a6-b16b-44af-b468-973805cc3c49"],"spl_set_id":["2105d1c1-54ef-4d1a-a63c-b1619e8b50db"],"substance_name":["MAGNESIUM CHLORIDE"],"unii":["02F3473H9O"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 200 mg/mL NDC 67457-134-50 50 mL Magnesium Chloride Injection 200 mg/mL (20% w/v) 2.951 mOsm/mL For Intravenous Use After Dilution Rx only Multiple-Dose Vial Each mL contains: Magnesium Chloride Hexahydrate 200 mg, Sodium Chloride 9 mg, Benzyl Alcohol 1% as a preservative, Water for Injection q.s. pH adjusted with Hydrochloric Acid and/or Sodium Hydroxide. Total osmolarity equivalent to 2.951 mOsm/mL. Contains 1.97 mEq of Mg ++ and CI¯ per mL. WARNING: DO NOT USE IF A PRECIPITATE IS PRESENT. Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.] Usual Dosage: See accompanying prescribing information. Manufactured for: Mylan Institutional LLC Morgantown, WV 26505 U.S.A. Manufactured by: Mylan Institutional Galway, Ireland MI:134:1C:R5 Mylan.com Magnesium Chloride Injection 200 mg/mL Carton Label"],"precautions":["PRECAUTIONS The usual precautions for parenteral administration should be observed. Administer with caution if flushing and sweating occurs. A preparation of a calcium salt should be readily available for intravenous injection to counteract potential serious signs of magnesium intoxication. As long as deep tendon reflexes are active it is probable that the patient will not develop respiratory paralysis. Respiration and blood pressure should be carefully observed during and after administration of Magnesium Chloride Injection. Pregnancy Animal reproduction studies have not been conducted with magnesium chloride. It is also not known whether magnesium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Magnesium Chloride should be given to a pregnant woman only if clearly needed."],"pregnancy":["Pregnancy Animal reproduction studies have not been conducted with magnesium chloride. It is also not known whether magnesium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Magnesium Chloride should be given to a pregnant woman only if clearly needed."],"set_id":"2105d1c1-54ef-4d1a-a63c-b1619e8b50db","spl_product_data_elements":["Magnesium Chloride magnesium chloride MAGNESIUM CHLORIDE MAGNESIUM CATION SODIUM CHLORIDE BENZYL ALCOHOL WATER HYDROCHLORIC ACID SODIUM HYDROXIDE"],"spl_unclassified_section":["ACTIONS Magnesium is the second most plentiful cation within cellular fluids. It is an important activator of many enzyme systems and deficits are accompanied by a variety of functional disturbances.","USUAL DOSAGE RANGE 1 to 40 grams daily. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit."],"version":"7","warnings":["WARNING Do not use if a precipitate is present."]}