{"active_ingredient":["Active ingredients Purpose AVOBENZON 2.5 % Sunscreen OCTINOXATE 7.4 % Sunscreen OCTOCRYLENE 2.0 % Sunscreen"],"active_ingredient_table":["<table width=\"50%\"><col width=\"50%\" align=\"left\" valign=\"bottom\"/><col width=\"50%\" align=\"center\" valign=\"bottom\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th> <content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>AVOBENZON 2.5 %</td><td>Sunscreen</td></tr><tr><td>OCTINOXATE 7.4 %</td><td>Sunscreen</td></tr><tr><td>OCTOCRYLENE 2.0 %</td><td>Sunscreen</td></tr></tbody></table>"],"do_not_use":["Do not use on damaged or broken skin"],"dosage_and_administration":["Directions For sunscreen use: apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every two hours Sun Protection Measures . Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m. – 2 p.m. wear long-sleeve shirts, pants, hats, and sunglasses children under 6 months: Ask a doctor"],"effective_time":"20260106","id":"47b9ba89-f802-c449-e063-6294a90a025b","inactive_ingredient":["Inactive Ingredients WATER∙GLYCERIN∙DIPROPYLENE GLYCOL∙BUTYLENE GLYCOL∙PHENYL TRIMETHICONE∙HYDROGENATED POLYDECENE∙SORBITOL∙MYRISTYL MYRISTATE∙DIMETHICONE∙SD ALCOHOL 40-B∙POLYBUTYLENE GLYCOL/PPG-9/1 COPOLYMER∙PETROLATUM∙STEARYL ALCOHOL∙STEARIC ACID∙SILICA∙BENTONITE∙PALMITIC ACID∙XANTHAN GUM∙PEG/PPG-17/4 DIMETHYL ETHER∙PHYTOSTERYL MACADAMIATE∙TOCOPHERYL ACETATE∙SAPINDUS MUKUROSSI PEEL EXTRACT∙UNCARIA GAMBIR EXTRACT∙SODIUM ACETYLATED HYALURONATE∙HYDROXYPROLINE∙THYMUS SERPILLUM EXTRACT∙CHLORELLA VULGARIS EXTRACT∙PEG-5 GLYCERYL STEARATE∙GLYCERYL STEARATE SE∙TRISODIUM EDTA∙POTASSIUM HYDROXIDE∙SODIUM METAPHOSPHATE∙AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER∙ALCOHOL∙SODIUM METABISULFITE∙BHT∙TOCOPHEROL∙PHENOXYETHANOL∙FRAGRANCE∙IRON OXIDES∙"],"indications_and_usage":["Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun"],"keep_out_of_reach_of_children":["Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M020"],"brand_name":["SHISEIDO BENEFIANCE WRINKLERESIST24 DAY"],"generic_name":["AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE"],"is_original_packager":[true],"manufacturer_name":["SHISEIDO AMERICAS CORPORATION"],"package_ndc":["58411-629-10"],"product_ndc":["58411-629"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"spl_id":["47b9ba89-f802-c449-e063-6294a90a025b"],"spl_set_id":["7d9c0f81-005f-4223-940e-a64143db5275"],"substance_name":["AVOBENZONE","OCTINOXATE","OCTOCRYLENE"],"unii":["G63QQF2NOX","4Y5P7MUD51","5A68WGF6WM"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 50 mL Bottle Carton SHISEIDO BENEFIANCE WrinkleResist24 Day Cream BROAD SPECTRUM SPF 18 SUNSCREEN 50mL NET WT. 1.8 OZ. PRINCIPAL DISPLAY PANEL - 50 mL Bottle Carton"],"purpose":["Active ingredients Purpose AVOBENZON 2.5 % Sunscreen OCTINOXATE 7.4 % Sunscreen OCTOCRYLENE 2.0 % Sunscreen"],"purpose_table":["<table width=\"50%\"><col width=\"50%\" align=\"left\" valign=\"bottom\"/><col width=\"50%\" align=\"center\" valign=\"bottom\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th> <content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>AVOBENZON 2.5 %</td><td>Sunscreen</td></tr><tr><td>OCTINOXATE 7.4 %</td><td>Sunscreen</td></tr><tr><td>OCTOCRYLENE 2.0 %</td><td>Sunscreen</td></tr></tbody></table>"],"questions":["Questions or comments? Call toll free 1-800-906-7503"],"set_id":"7d9c0f81-005f-4223-940e-a64143db5275","spl_product_data_elements":["SHISEIDO BENEFIANCE WRINKLERESIST24 DAY AVOBENZONE, OCTINOXATE, and OCTOCRYLENE WATER GLYCERIN DIPROPYLENE GLYCOL BUTYLENE GLYCOL PHENYL TRIMETHICONE HYDROGENATED POLYDECENE TYPE I SORBITOL MYRISTYL MYRISTATE DIMETHICONE PETROLATUM STEARYL ALCOHOL STEARIC ACID SILICON DIOXIDE BENTONITE PALMITIC ACID XANTHAN GUM PEG/PPG-17/4 DIMETHYL ETHER PHYTOSTERYL MACADAMIATE .ALPHA.-TOCOPHEROL ACETATE, DL- SAPINDUS MUKOROSSI FRUIT RIND SODIUM ACETYLATED HYALURONATE HYDROXYPROLINE CHLORELLA VULGARIS PEG-5 GLYCERYL STEARATE GLYCERYL MONOSTEARATE EDETATE TRISODIUM POTASSIUM HYDROXIDE SODIUM POLYMETAPHOSPHATE AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER ALCOHOL SODIUM METABISULFITE BUTYLATED HYDROXYTOLUENE .ALPHA.-TOCOPHEROL PHENOXYETHANOL FERRIC OXIDE RED FERRIC OXIDE YELLOW FERROSOFERRIC OXIDE AVOBENZONE AVOBENZONE OCTINOXATE OCTINOXATE OCTOCRYLENE OCTOCRYLENE"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if rash occurs."],"storage_and_handling":["Other information Protect this product in this container from excessive heat and direct sun."],"version":"3","warnings":["Warnings For external use only Do not use on damaged or broken skin When using this product keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if rash occurs. Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product keep out of eyes. Rinse with water to remove."]}