{"active_ingredient":["Active ingredients Purpose AVOBENZON 2.5 % Sunscreen OCTINOXATE 7.4 % Sunscreen OCTOCRYLENE 2.0 % Sunscreen"],"active_ingredient_table":["<table width=\"55%\"><col width=\"75%\" align=\"left\" valign=\"top\"/><col width=\"25%\" align=\"left\" valign=\"top\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th align=\"center\"><content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>AVOBENZON 2.5 %</td><td>Sunscreen</td></tr><tr><td>OCTINOXATE 7.4 %</td><td>Sunscreen</td></tr><tr><td>OCTOCRYLENE 2.0 %</td><td>Sunscreen</td></tr></tbody></table>"],"do_not_use":["Do not use on damaged or broken skin"],"dosage_and_administration":["Directions For sunscreen use: apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every two hours Sun Protection Measures . Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m. – 2 p.m. wear long-sleeve shirts, pants, hats, and sunglasses children under 6 months: Ask a doctor"],"effective_time":"20260106","id":"47baa86d-0053-fbb4-e063-6394a90ad8d0","inactive_ingredient":["Inactive Ingredients WATER•GLYCERIN•SD ALCOHOL 40-B•DIPROPYLENE GLYCOL•XYLITOL•BUTYLENE GLYCOL•SILICA•POLYBUTYLENE GLYCOL/PPG-9/1 COPOLYMER•HYDROGENATED POLYDECENE•PEG-60 GLYCERYL ISOSTEARATE•TRIISOSTEARIN•DIMETHICONE•DIPHENYLSILOXY PHENYL TRIMETHICONE•XANTHAN GUM•PEG/PPG-17/4 DIMETHYL ETHER•PHYTOSTERYL MACADAMIATE•TOCOPHERYL ACETATE•SAPINDUS MUKUROSSI PEEL EXTRACT•UNCARIA GAMBIR EXTRACT•SODIUM ACETYLATED HYALURONATE•HYDROXYPROLINE•THYMUS SERPILLUM EXTRACT•CHLORELLA VULGARIS EXTRACT•STEARIC ACID•GLYCERYL STEARATE SE•BEHENYL ALCOHOL•ISOSTEARIC ACID•BEHENIC ACID•BEHENETH-20•TRIETHANOLAMINE•CELLULOSE GUM•DISODIUM EDTA•SODIUM METAPHOSPHATE•ALCOHOL•BHT•TOCOPHEROL•PHENOXYETHANOL•FRAGRANCE•IRON OXIDES•"],"indications_and_usage":["Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun"],"keep_out_of_reach_of_children":["Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M020"],"brand_name":["SHISEIDO BENEFIANCE WRINKLERESIST24 DAY"],"generic_name":["AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE"],"is_original_packager":[true],"manufacturer_name":["SHISEIDO AMERICAS CORPORATION"],"package_ndc":["58411-628-10"],"product_ndc":["58411-628"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"spl_id":["47baa86d-0053-fbb4-e063-6394a90ad8d0"],"spl_set_id":["d308d578-c881-4c10-8c79-9e3cd58b694c"],"substance_name":["AVOBENZONE","OCTINOXATE","OCTOCRYLENE"],"unii":["G63QQF2NOX","4Y5P7MUD51","5A68WGF6WM"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 75 mL Bottle Carton SHISEIDO BENEFIANCE WrinkleResist24 Day Emulsion BROAD SPECTRUM SPF 18 SUNSCREEN 75mL 2.5 FL. OZ. Principal Display Panel - 75 mL Bottle Carton"],"purpose":["Active ingredients Purpose AVOBENZON 2.5 % Sunscreen OCTINOXATE 7.4 % Sunscreen OCTOCRYLENE 2.0 % Sunscreen"],"purpose_table":["<table width=\"55%\"><col width=\"75%\" align=\"left\" valign=\"top\"/><col width=\"25%\" align=\"left\" valign=\"top\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th align=\"center\"><content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>AVOBENZON 2.5 %</td><td>Sunscreen</td></tr><tr><td>OCTINOXATE 7.4 %</td><td>Sunscreen</td></tr><tr><td>OCTOCRYLENE 2.0 %</td><td>Sunscreen</td></tr></tbody></table>"],"questions":["Questions or comments? Call toll free 1-800-906-7503"],"set_id":"d308d578-c881-4c10-8c79-9e3cd58b694c","spl_product_data_elements":["SHISEIDO BENEFIANCE WRINKLERESIST24 DAY AVOBENZONE, OCTINOXATE, and OCTOCRYLENE WATER GLYCERIN DIPROPYLENE GLYCOL XYLITOL BUTYLENE GLYCOL SILICON DIOXIDE HYDROGENATED POLYDECENE TYPE I PEG-60 GLYCERYL ISOSTEARATE TRIISOSTEARIN DIMETHICONE DIPHENYLSILOXY PHENYL TRIMETHICONE XANTHAN GUM PEG/PPG-17/4 DIMETHYL ETHER PHYTOSTERYL MACADAMIATE .ALPHA.-TOCOPHEROL ACETATE, DL- SAPINDUS MUKOROSSI FRUIT RIND UNCARIA GAMBIR WHOLE SODIUM ACETYLATED HYALURONATE HYDROXYPROLINE CHLORELLA VULGARIS STEARIC ACID GLYCERYL MONOSTEARATE DOCOSANOL ISOSTEARIC ACID BEHENIC ACID BEHENETH-20 TROLAMINE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED EDETATE DISODIUM SODIUM POLYMETAPHOSPHATE ALCOHOL BUTYLATED HYDROXYTOLUENE .ALPHA.-TOCOPHEROL PHENOXYETHANOL FERRIC OXIDE RED FERRIC OXIDE YELLOW FERROSOFERRIC OXIDE AVOBENZONE AVOBENZONE OCTINOXATE OCTINOXATE OCTOCRYLENE OCTOCRYLENE"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use and ask a doctor if rash occurs."],"storage_and_handling":["Other information Protect this product in this container from excessive heat and direct sun."],"version":"3","warnings":["Warnings For external use only Do not use on damaged or broken skin When using this product keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if rash occurs. Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product keep out of eyes. Rinse with water to remove."]}