{"active_ingredient":["Active ingredient Benzoyl peroxide 2.5%"],"do_not_use":["Do not use if you have very sensitive skin are sensitive to benzoyl peroxide."],"dosage_and_administration":["Directions Sensitivity Test for a New User. Apply product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, follow the directions stated below. cover the entire affected area with a thin layer and rinse thoroughly one to three times daily because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor."],"effective_time":"20260107","id":"47d2927b-b68b-90ff-e063-6294a90a34f6","inactive_ingredient":["Inactive ingredients water, sodium cocoyl isethionate, glycerin, paraffin, lauryl/myristyl benzoate, coconut acid, butylene glycol, acrylates/C10-30 alkyl acrylate crosspolymer, phenoxyethanol, sodium isethionate, sodium hydroxide, fragrance, dimethicone, linoleic acid, ethylhexylglycerin, glycolic acid, linolenic acid"],"indications_and_usage":["Use for the management of acne"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M006"],"brand_name":["Proactivplus Skin Smoothing Exfoliator"],"generic_name":["BENZOYL PEROXIDE"],"is_original_packager":[true],"manufacturer_name":["Alchemee, LLC"],"package_ndc":["11410-011-68","11410-011-82"],"product_ndc":["11410-011"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"spl_id":["47d2927b-b68b-90ff-e063-6294a90a34f6"],"spl_set_id":["b56b63d6-5635-4fd4-9517-8b08c3cbf9aa"],"substance_name":["BENZOYL PEROXIDE"],"unii":["W9WZN9A0GM"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 60 mL Carton proactiv + Skin Smoothing Exfoliator 2 FL. OZ. (60 mL) benzoyl peroxide acne treatment unit carton image"],"purpose":["Purpose Acne treatment"],"questions":["Questions or comments? 1-800-950-4695"],"set_id":"b56b63d6-5635-4fd4-9517-8b08c3cbf9aa","spl_product_data_elements":["Proactivplus Skin Smoothing Exfoliator BENZOYL PEROXIDE WATER SODIUM COCOYL ISETHIONATE GLYCERIN LAURYL/MYRISTYL BENZOATE COCONUT ACID LINOLEIC ACID LINOLENIC ACID BUTYLENE GLYCOL DIMETHICONE ETHYLHEXYLGLYCERIN CARBOMER COPOLYMER TYPE A (ALLYL PENTAERYTHRITOL CROSSLINKED) GLYCOLIC ACID SODIUM ISETHIONATE SODIUM HYDROXIDE PHENOXYETHANOL PARAFFIN BENZOYL PEROXIDE BENZOYL PEROXIDE"],"spl_unclassified_section":["Drug Facts","Distributed by Alchemee LLC, Santa Monica, CA 90401 Made in the USA of Foreign and Domestic Components Questions? 1-800-950-4695 • proactiv.com • Proactiv is a registered trademark of Taro Pharmaceuticals U.S.A., Inc."],"stop_use":["Stop use and ask a doctor if irritation becomes severe."],"version":"10","warnings":["Warnings For external use only When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. Do not use if you have very sensitive skin are sensitive to benzoyl peroxide. Stop use and ask a doctor if irritation becomes severe. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration."]}