{"active_ingredient":["Active ingredients Active ingredients (in each tablet) Purposes Aspirin 325 mg (NSAID)*…….……………….Pain reliever/fever reducer Dextromethorphan hydrobromide 10 mg……………Cough suppressant Phenylephrine bitartrate 7.8 mg.......……....…...…..Nasal decongestant *nonsteroidal anti-inflammatory drug"],"ask_doctor":["Ask a doctor Ask a doctor before use if ● stomach bleeding warning applies to you ● you have a history of stomach problems, such as heartburn ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ● you are taking a diuretic ● you have ● asthma ● thyroid disease ● diabetes ● cough with excessive phlegm (mucus) ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema ● a sodium-restricted diet"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist Ask a doctor or pharmacist before use if you are · taking a prescription drug for · gout · diabetes · arthritis"],"do_not_use":["Do not use Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age"],"dosage_and_administration":["Directions Directions ● adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 8 tablets in 24 hours or as directed by a doctor. ● children under 12 years: do not use"],"effective_time":"20260108","id":"47e317c2-ea4e-8cce-e063-6394a90a9182","inactive_ingredient":["Inactive ingredients Inactive ingredients anhydrous citric acid, calcium silicate, dimethicone, FD&C red #40, FD&C yellow #6, flavor, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose"],"indications_and_usage":["Uses Uses · temporarily relieves these symptoms due to a cold with cough: · minor aches and pains · headache · cough · nasal and sinus congestion · sore throat · temporarily reduces fever"],"keep_out_of_reach_of_children":["Keep out of reach Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M012"],"brand_name":["Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy"],"generic_name":["ASPRIN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE BITARTRATE"],"is_original_packager":[true],"manufacturer_name":["Bayer HealthCare LLC."],"nui":["N0000000160","N0000008836","M0001335","N0000175722","N0000175578","N0000008832"],"package_ndc":["0280-0024-01","0280-0024-02"],"pharm_class_cs":["Anti-Inflammatory Agents, Non-Steroidal [CS]"],"pharm_class_epc":["Nonsteroidal Anti-inflammatory Drug [EPC]","Platelet Aggregation Inhibitor [EPC]"],"pharm_class_moa":["Cyclooxygenase Inhibitors [MoA]"],"pharm_class_pe":["Decreased Prostaglandin Production [PE]","Decreased Platelet Aggregation [PE]"],"product_ndc":["0280-0024"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1536498"],"spl_id":["47e317c2-ea4e-8cce-e063-6394a90a9182"],"spl_set_id":["a355d987-77ce-9e32-e053-2995a90a6431"],"substance_name":["ASPIRIN","PHENYLEPHRINE BITARTRATE","DEXTROMETHORPHAN HYDROBROMIDE"],"unii":["R16CO5Y76E","27O3Q5ML57","9D2RTI9KYH"],"upc":["0016500590965"]},"other_safety_information":["Other information Other information ● each tablet contains : potassium 80 mg; sodium 356 mg ● store at room temperature. Avoid excessive heat."],"package_label_principal_display_panel":["Carton 20 count Alka-Seltzer Plus® SEVERE Cold CITRUS POWERFAST™ FIZZ NEW IMPROVED FLAVOR NON-DROWSY ASPIRIN (NSAID) / Pain Reliever-Fever Reducer Dextromehorphan HBr / Cough Suppressant Phenylephrine Bitartrate / Nasal Decongestant Fever + Body Ache Nasal Congestion Sinus Pressure Sore Throat Cough 20 EFFERVESCENT TABLETS ASP Cold 1 ASP Cold 2"],"pregnancy_or_breast_feeding":["Pregnant or breast feeding If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery."],"purpose":[""],"questions":["Questions Questions or comments? 1-800-986-0369 (Mon-Fri 9AM – 5PM EST)"],"set_id":"a355d987-77ce-9e32-e053-2995a90a6431","spl_product_data_elements":["Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy asprin, dextromethorphan hydrobromide, phenylephrine bitartrate MANNITOL SODIUM BICARBONATE ASPIRIN ASPIRIN PHENYLEPHRINE BITARTRATE PHENYLEPHRINE CALCIUM SILICATE DIMETHICONE FD&C RED NO. 40 ANHYDROUS CITRIC ACID DEXTROMETHORPHAN HYDROBROMIDE DEXTROMETHORPHAN FD&C YELLOW NO. 6 POVIDONE, UNSPECIFIED SUCRALOSE POTASSIUM BICARBONATE ASP Speckled"],"spl_unclassified_section":["Drug Facts"],"stop_use":["Stop use Stop use and ask a doctor if · an allergic reaction occurs. Seek medical help right away. ● you experience any of the following signs of stomach bleeding ● feel faint ● vomit blood ● have bloody or black stools ● have stomach pain that does not get better · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · ringing in the ears or a loss of hearing occurs · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs"],"version":"5","warnings":["Warnings Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include: · hives · facial swelling · asthma (wheezing) · shock Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you ● are age 60 or older ● have had stomach ulcers or bleeding problems ● take a blood thinning (anticoagulant) or steroid drug ● take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ● have 3 or more alcoholic drinks every day while using this product ● take more or for a longer time than directed Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age Ask a doctor Ask a doctor before use if ● stomach bleeding warning applies to you ● you have a history of stomach problems, such as heartburn ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ● you are taking a diuretic ● you have ● asthma ● thyroid disease ● diabetes ● cough with excessive phlegm (mucus) ● difficulty in urination due to enlargement of the prostate gland ● persistent or chronic cough such as occurs with smoking, asthma, or emphysema ● a sodium-restricted diet Ask a doctor or pharmacist Ask a doctor or pharmacist before use if you are · taking a prescription drug for · gout · diabetes · arthritis When using this product When using this product do not exceed recommended dosage Stop use Stop use and ask a doctor if · an allergic reaction occurs. Seek medical help right away. ● you experience any of the following signs of stomach bleeding ● feel faint ● vomit blood ● have bloody or black stools ● have stomach pain that does not get better · pain, cough, or nasal congestion gets worse or lasts more than 7 days · fever gets worse or lasts more than 3 days · redness or swelling is present · new symptoms occur · ringing in the ears or a loss of hearing occurs · cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. · nervousness, dizziness, or sleeplessness occurs Pregnant or breast feeding If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product When using this product do not exceed recommended dosage"]}