{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e32c0d-afe7-af72-e063-6394a90af9cf","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, cellulose gum, sodium saccharin, carbomer, charcoal powder, sucralose, polysorbate 80, mica, titanium dioxide"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Brilliance Charcoal"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Procter & Gamble Manfuacturing Company"],"package_ndc":["37000-989-39","37000-989-35","37000-989-46"],"product_ndc":["37000-989"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e32c0d-afe7-af72-e063-6394a90af9cf"],"spl_set_id":["b7882679-339c-554f-e053-2995a90afa7f"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 130 g Carton LARGE SIZE CREST 3D WHITE NEW WT 4.6 OZ (130 g) FLUORIDE ANTICAVITY TOOTHPASTE ENAMEL SAFE BRILLIANCE CHARCOAL MINT EXTRA STRENGTH WHITENING WHITER TEETH IN 3 DAYS Artwork"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"b7882679-339c-554f-e053-2995a90afa7f","spl_product_data_elements":["Crest 3D White Brilliance Charcoal Sodium Fluoride COCAMIDOPROPYL BETAINE SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS POVIDONE, UNSPECIFIED POLYETHYLENE GLYCOL 300 ACTIVATED CHARCOAL WATER SACCHARIN SODIUM HYDRATED SILICA SODIUM LAURYL SULFATE SUCRALOSE TITANIUM DIOXIDE MICA SODIUM FLUORIDE FLUORIDE ION SODIUM HEXAMETAPHOSPHATE CARRAGEENAN GLYCERIN XANTHAN GUM"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"10","warnings":["Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}