{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e347f8-eb74-9c1c-e063-6294a90ab479","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, xanthan gum. sodium saccharin, cellulose gum, carbomer, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Premium Plus Deep Clean Active Foam"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-994-72","37000-994-52","37000-994-15"],"product_ndc":["37000-994"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e347f8-eb74-9c1c-e063-6294a90ab479"],"spl_set_id":["b851fe5c-d904-12da-e053-2a95a90a86f9"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 204 g Tube Carton Crest ® plus PREMIUM ANTICAVITY FLUORIDE TOOTHPASTE NET WT 7.2 OZ (204 g) ACTIVE FOAM + WHITENING DEEP CLEAN WHITENS & PREVENTS TARTAR BUILDUP foaming mint 994"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"b851fe5c-d904-12da-e053-2a95a90a86f9","spl_product_data_elements":["Crest Premium Plus Deep Clean Active Foam Sodium Fluoride XANTHAN GUM TITANIUM DIOXIDE FD&C BLUE NO. 1 WATER SORBITOL HYDRATED SILICA SODIUM ACID PYROPHOSPHATE SODIUM LAURYL SULFATE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM SODIUM HYDROXIDE SACCHARIN SODIUM SODIUM FLUORIDE FLUORIDE ION CARBOXYPOLYMETHYLENE"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"8","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}