{"active_ingredient":["Drug Facts Active ingredient Stannous fluoride 0.454% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. & older: apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least 1 minute twice a day (morning and evening) or as recommended by a dentist. Make sure to brush all sensitive areas of the teeth. do not swallow children under 12 yrs. of age: ask a dentist"],"effective_time":"20260108","id":"47e38bc0-81d7-255e-e063-6294a90a22de","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, sodium lauryl sulfate, sodium gluconate, carrageenan, flavor, sodium citrate, xanthan gum, zinc citrate, glycine, sodium hydroxide, stannous chloride, sodium saccharin, sucralose, titanium dioxide, blue 1"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact"],"keep_out_of_reach_of_children":["Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Pro Health Sensitive and Enamel Shield"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-783-43","69423-783-26","69423-783-46","69423-783-21"],"product_ndc":["69423-783"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["47e38bc0-81d7-255e-e063-6294a90a22de"],"spl_set_id":["fb48b15c-f821-e5cd-e053-6294a90ac64c"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"]},"package_label_principal_display_panel":["Principal Display Panel - 121 g tube in carton Crest ® PRO-HEALTH FLUORIDE TOOTHPASTE FOR ANTICAVITY, ANTIGINGIVITIS AND SENSITIVE TEETH CAVITIES GUM ENAMEL SENSITIVITY PLAQUE TARTAR WHITENS FRESHENS BREATH NET WT 2.6 OZ (73 g) FORMULATED WITH AMINO ACID GLYCINE SENSITIVE & ENAMEL SHIELD PROTECTS 100% OF THE WHOLE MOUTH 1.5X MORE FREE VS 0.85 OZ 69423-783"],"purpose":["Purposes Anticavity, antigingivitis, antisensitivity toothpaste"],"questions":["Questions? 1-800-594-4158"],"set_id":"fb48b15c-f821-e5cd-e053-6294a90ac64c","spl_product_data_elements":["Crest Pro Health Sensitive and Enamel Shield Stannous fluoride ZINC CITRATE SODIUM LAURYL SULFATE TITANIUM DIOXIDE SODIUM CITRATE STANNOUS CHLORIDE SUCRALOSE SORBITOL GLYCINE SODIUM HYDROXIDE WATER HYDRATED SILICA CARRAGEENAN XANTHAN GUM SACCHARIN SODIUM SODIUM GLUCONATE STANNOUS FLUORIDE FLUORIDE ION FD&C BLUE NO. 1"],"spl_unclassified_section":["DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"stop_use":["Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care."],"version":"7","warnings":["When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist. Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care. Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"warnings_and_cautions":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist this Crest is specially formulated to help prevent staining see your dentist regularly"],"when_using":["When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist."]}