{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e3b7c7-6aca-6a90-e063-6294a90a4cfe","inactive_ingredient":["Inactive ingredients sorbitol, water, hydrated silica, sodium lauryl sulfate, trisodium phosphate, flavor, cellulose gum, sodium phosphate, carbomer, sodium saccharin, titanium dioxide, blue 1"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 4in1"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-852-24"],"product_ndc":["69423-852"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e3b7c7-6aca-6a90-e063-6294a90a4cfe"],"spl_set_id":["ce545406-3c4f-1ba7-e053-2a95a90a91ac"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 68 g Carton HELPS PREVENT CAVITIES Crest FLUORIDE ANTICAVITY TOOTHPASTE NET WT 2.4 OZ (68 g) 4in1 Whitens Protects Freshens Cleans Paste 69423852"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"ce545406-3c4f-1ba7-e053-2a95a90a91ac","spl_product_data_elements":["Crest 4in1 Sodium Fluoride SODIUM PHOSPHATE TITANIUM DIOXIDE FD&C BLUE NO. 1 SACCHARIN SODIUM CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED FORM SORBITOL WATER HYDRATED SILICA SODIUM FLUORIDE FLUORIDE ION CARBOXYPOLYMETHYLENE SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS SODIUM LAURYL SULFATE"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati OH 45202"],"version":"6","warnings":["Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}