{"active_ingredient":["Drug Facts Active ingredient Stannous fluoride 0.454% (0.14% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. & older: apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least 1 minute twice a day (morning and evening) or as recommended by a dentist. Make sure to brush all sensitive areas of the teeth. do not swallow children under 12 yrs. of age: ask a dentist"],"effective_time":"20260108","id":"47e48583-7045-240e-e063-6394a90a6952","inactive_ingredient":["Inactive ingredients water, sorbitol, hydrated silica, sodium lauryl sulfate, sodium gluconate, carrageenan, flavor, sodium citrate, xanthan gum, zinc citrate, sodium saccharin, sodium hydroxide, stannous chloride, charcoal powder, sucralose"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact"],"keep_out_of_reach_of_children":["Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Pro Health Advanced Whitening Charcoal"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-860-46"],"product_ndc":["69423-860"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["47e48583-7045-240e-e063-6394a90a6952"],"spl_set_id":["d6f68485-b92f-41c7-e053-2995a90a4fe5"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"]},"package_label_principal_display_panel":["Principal Display Panel - 130 g tube in carton Crest ® FLUORIDE TOOTHPASTE FOR ANTICAVITY, ANTIGINGIVITIS AND SENSITIVE TEETH CAVITIES GINGIVITIS ENAMEL SENSITIVITY PLAQUE TARTAR WHITENING FRESHENS BREATH NET WT 4.6 OZ (130 g) DENTIST DESIGNED CLINICALLY PROVEN* PRO HEALTH™ ADVANCED STANNOUS FLUORIDE HELPS PREVENT PLAQUE GROWTH TO STOP ISSUES BEFORE THEY START.** WHITENING + CHARCOAL Crest Pro Health Whitening + Charcoal"],"purpose":["Purposes Anticavity, antigingivitis, antisensitivity toothpaste"],"questions":["Questions? 1-800-594-4158"],"set_id":"d6f68485-b92f-41c7-e053-2995a90a4fe5","spl_product_data_elements":["Crest Pro Health Advanced Whitening Charcoal Stannous fluoride ACTIVATED CHARCOAL SODIUM CITRATE SUCRALOSE STANNOUS CHLORIDE WATER HYDRATED SILICA CARRAGEENAN SODIUM GLUCONATE XANTHAN GUM ZINC CITRATE SODIUM LAURYL SULFATE SORBITOL SODIUM HYDROXIDE SACCHARIN SODIUM STANNOUS FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"stop_use":["Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care."],"version":"5","warnings":["When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist. Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care. Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"warnings_and_cautions":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist this Crest is specially formulated to help prevent staining see your dentist regularly"],"when_using":["When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist."]}