{"active_ingredient":["Drug Facts Active ingredient Stannous fluoride 0.454% (0.16% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. & older: apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least 1 minute twice a day (morning and evening) or as recommended by a dentist. Make sure to brush all sensitive areas of the teeth. do not swallow children under 12 yrs. of age: ask a dentist"],"effective_time":"20260108","id":"47e48dff-09e0-2ea2-e063-6394a90a8e41","inactive_ingredient":["Inactive ingredients glycerin, hydrated silica, sodium hexametaphosphate, propylene glycol, PEG-6, water, zinc lactate, flavor, sodium lauryl sulfate, sodium gluconate, sodium saccharin, trisodium phosphate, xanthan gum, PVP, carrageenan, cocamidopropyl betaine, blue 1"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact"],"keep_out_of_reach_of_children":["Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Pro Health Advanced Gum Protection"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["69423-867-51","69423-867-35","69423-867-94","69423-867-85"],"product_ndc":["69423-867"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416784"],"spl_id":["47e48dff-09e0-2ea2-e063-6394a90a8e41"],"spl_set_id":["d7729dde-c828-34e6-e053-2a95a90a5ee6"],"substance_name":["STANNOUS FLUORIDE"],"unii":["3FTR44B32Q"]},"package_label_principal_display_panel":["Principal Display Panel - 144 g tube in carton Crest ® FLUORIDE TOOTHPASTE FOR ANTICAVITY, ANTIGINGIVITIS AND SENSITIVE TEETH CAVITIES GINGIVITIS ENAMEL SENSITIVITY PLAQUE TARTAR WHITENING FRESHENS BREATH NET WT 5.1 OZ (144 g) DENTIST DESIGNED CLINICALLY PROVEN* PRO HEALTH™ ADVANCED HELPS PREVENT PLAQUE GROWTH TO STOP ISSUES BEFORE THEY START.** GUM PROTECTION Crest Pro Health Advanced Gum Protection"],"purpose":["Purposes Anticavity, antigingivitis antisensitivity toothpaste"],"questions":["Questions? 1-800-594-4158"],"set_id":"d7729dde-c828-34e6-e053-2a95a90a5ee6","spl_product_data_elements":["Crest Pro Health Advanced Gum Protection Stannous fluoride POVIDONE, UNSPECIFIED FD&C BLUE NO. 1 SODIUM POLYMETAPHOSPHATE PROPYLENE GLYCOL POLYETHYLENE GLYCOL 300 ZINC LACTATE SODIUM GLUCONATE GLYCERIN COCAMIDOPROPYL BETAINE WATER HYDRATED SILICA CARRAGEENAN XANTHAN GUM SODIUM LAURYL SULFATE SACCHARIN SODIUM SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS STANNOUS FLUORIDE FLUORIDE ION"],"spl_unclassified_section":["DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"stop_use":["Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care."],"version":"10","warnings":["When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist. Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care. Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"warnings_and_cautions":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist this Crest is specially formulated to help prevent staining see your dentist regularly"],"when_using":["When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist."]}