{"active_ingredient":["Active ingredient Cetylpyridinium chloride 0.1%"],"ask_doctor_or_pharmacist":["Ask a dentist if symptoms persist or condition worsens after regular use."],"dosage_and_administration":["Directions use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use adults and children 12 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day do not swallow supervise use in children children under 12 years of age: do not use"],"effective_time":"20260108","id":"47e49363-ea07-b3c5-e063-6294a90acf3c","inactive_ingredient":["Inactive ingredients water, glycerin, hydrogen peroxide, flavor, sucralose, poloxamer 407"],"indications_and_usage":["Uses helps prevent and reduce plaque and gingivitis helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums"],"keep_out_of_reach_of_children":["Keep out of reach of children under 12 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M022"],"brand_name":["Crest Pro-Health Clinical"],"generic_name":["CETYLPYRIDINIUM CHLORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-843-08","37000-843-16","37000-843-32"],"product_ndc":["37000-843"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["1291375","1433894"],"spl_id":["47e49363-ea07-b3c5-e063-6294a90acf3c"],"spl_set_id":["0a295ee0-55c2-4f21-8f0a-70efc0e51694"],"substance_name":["CETYLPYRIDINIUM CHLORIDE"],"unii":["D9OM4SK49P"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 473 mL Bottle Label Crest ® PRO-HEALTH™ CPC ANTIGINGIVITIS/ANTIPLAQUE ORAL RINSE ALCOHOL FREE CLINICAL OUR MOST ADVANCED RINSE EVER Reduces plaque & even helps prevent plaque regrowth Helps prevent & even helps reverse gingivitis in 2 weeks Kills 99% of germs to improve breath DEEP CLEAN MINT 473mL (16 FL OZ) 843"],"purpose":["Purpose Antigingivitis/Antiplaque"],"questions":["Questions? 1–800–285–9139"],"set_id":"0a295ee0-55c2-4f21-8f0a-70efc0e51694","spl_product_data_elements":["Crest Pro-Health Clinical Cetylpyridinium chloride GLYCERIN HYDROGEN PEROXIDE SUCRALOSE POLOXAMER 407 CETYLPYRIDINIUM CHLORIDE CETYLPYRIDINIUM WATER Clear"],"spl_unclassified_section":["Drug Facts","Dist. by Procter & Gamble, Cincinnati OH 45202"],"version":"10","warnings":["Warnings Ask a dentist if symptoms persist or condition worsens after regular use. Keep out of reach of children under 12 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}