{"active_ingredient":["Active ingredient Sodium fluoride 0.243% (0.16% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"],"effective_time":"20260108","id":"47e49f8f-fd96-9aa4-e063-6294a90a5e29","inactive_ingredient":["Inactive ingredients glycerin, hydrated silica, sodium hexametaphosphate, water, PEG-6, flavor, trisodium phosphate, sodium lauryl sulfate, carrageenan, cocamidopropyl betaine, sodium saccharin, PEG-20M or PEG-23M, xanthan gum, sucralose, mica, titanium dioxide"],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Brilliance"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-873-04","37000-873-08","37000-873-12","37000-873-85","37000-873-39","37000-873-27","37000-873-52","37000-873-24","37000-873-35","37000-873-93","37000-873-78","37000-873-46","37000-873-23","37000-873-34","37000-873-42"],"product_ndc":["37000-873"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["891775"],"spl_id":["47e49f8f-fd96-9aa4-e063-6294a90a5e29"],"spl_set_id":["8e189fbd-5094-4398-b96c-8f95d89b9cdd"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"],"upc":["0037000926924"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 24g Tube Carton CREST 3D WHITE BRILLIANCE VIBRANT PEPPERMINT EXTRA STRENGTH WHITENING WHITER TEETH IN 3 DAYS NET WT 0.85OZ (24 g) FLUORIDE ANTICAVITY TOOTHPASTE ENAMEL SAFE Artwork"],"purpose":["Purpose Anticavity toothpaste"],"questions":["Questions? 1-800-492-7378"],"set_id":"8e189fbd-5094-4398-b96c-8f95d89b9cdd","spl_product_data_elements":["Crest 3D White Brilliance sodium fluoride XANTHAN GUM SUCRALOSE MICA TITANIUM DIOXIDE SODIUM FLUORIDE FLUORIDE ION GLYCERIN HYDRATED SILICA SODIUM POLYMETAPHOSPHATE WATER SACCHARIN SODIUM POLYETHYLENE GLYCOL 300 SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS SODIUM LAURYL SULFATE CARRAGEENAN COCAMIDOPROPYL BETAINE"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"21","warnings":["Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}