{"active_ingredient":["Active ingredient Stannous fluoride 0.454% (0.15% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 12 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. do not swallow children under 12 yrs. of age: ask a dentist"],"effective_time":"20260108","id":"47e4a85d-a3e6-ba6a-e063-6294a90a251d","inactive_ingredient":["Inactive ingredients glycerin, hydrated silica, water, zinc lactate, sodium lauryl sulfate, trisodium phosphate, flavor, sodium gluconate, sodium saccharin, xanthan gum, cellulose gum, sodium hydroxide, mica, titanium dioxide"],"indications_and_usage":["Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis"],"keep_out_of_reach_of_children":["Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest 3D White Brilliance Daily Cleansing and Whitening System"],"generic_name":["STANNOUS FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-863-04"],"product_ndc":["37000-863"],"product_type":["HUMAN OTC DRUG"],"rxcui":["416784"],"spl_id":["47e4a85d-a3e6-ba6a-e063-6294a90a251d"],"spl_set_id":["89a6fb36-5109-47f1-95ad-9381471ceeef"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - Kit Carton DAILY WHITENING 2-STEP TREATMENT Crest BRILLIANCE 3D WHITE WHITENING 2-STEP FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS - WHITENING GEL KEEPS YOUR SMILE UP TO 99% AS WHITE AS A PROFESSIONAL POLISH NET WT 1 TUBE 4.0 OZ (113 g) & 1 TUBE 2.3 OZ (65 g) Label"],"purpose":["Purposes Anticavity, antigingivitis toothpaste"],"questions":["Questions? 1 (800) 492-7378"],"set_id":"89a6fb36-5109-47f1-95ad-9381471ceeef","spl_product_data_elements":["Crest 3D White Brilliance Daily Cleansing and Whitening System Stannous Fluoride Crest 3D White Step 1 Purifying Cleanser Stannous Fluoride GLYCERIN HYDRATED SILICA WATER ZINC LACTATE SODIUM LAURYL SULFATE SODIUM GLUCONATE SACCHARIN SODIUM XANTHAN GUM CARBOXYMETHYLCELLULOSE SODIUM SODIUM HYDROXIDE MICA TITANIUM DIOXIDE STANNOUS FLUORIDE FLUORIDE ION Crest 3D White Step 2 Whitening Gel WATER GLYCERIN HYDROGEN PEROXIDE SODIUM ACID PYROPHOSPHATE SUCRALOSE SODIUM HYDROXIDE"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"storage_and_handling":["Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist see your dentist regularly"],"version":"9","warnings":["Warning Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}