{"active_ingredient":["Active ingredient Sodium Fluoride 0.02% (0.01% w/v fluoride ion)"],"dosage_and_administration":["Directions Adults and children 12 years & older: Use twice a day after brushing your teeth with a toothpaste. Vigorously swish 10 mL (2 teaspoonfuls) of rinse between your teeth for 1 minute and then spit out. Do not swallow the rinse. Do not eat or drink for 30 minutes after rinsing. Instruct children under 12 years of age in good rinsing habits (to minimize swallowing). Supervise children as necessary until capable of using without supervision. Children under 12 years of age: consult a dentist or doctor."],"effective_time":"20260108","id":"47e4a9bf-9cbb-4bc6-e063-6394a90abac4","inactive_ingredient":["Inactive ingredients water, glycerin, hydrogen peroxide, poloxamer 407, flavor, polysorbate 80, sodium saccharin, sucralose, phosphoric acid, disodium phosphate"],"indications_and_usage":["Use Aids in the prevention of dental cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["Crest Pro-Health Advanced w/Extra Whitening"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["The Procter & Gamble Manufacturing Company"],"package_ndc":["37000-867-01","37000-867-02","37000-867-29"],"product_ndc":["37000-867"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["313029","1658137"],"spl_id":["47e4a9bf-9cbb-4bc6-e063-6394a90abac4"],"spl_set_id":["2c1c5563-0b7e-4c7c-b49f-3d72e078cd28"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"],"upc":["0037000943211"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 473 mL Bottle Label +FLUORIDE CREST PRO-HEALTH ADVANCED ANTICAVITY FLUORIDE RINSE EXTRA WHITENING ALCOHOL FREE IMPORTANT: Read directions for proper use. KILLS BAD BREATH GERMS WHITER SMILE** IN 7 DAYS HELPS PREVENT CAVITIES STRENGTHENS ENAMEL FRESHENS BREATH 473mL (16 FL OZ) Label"],"purpose":["Purpose Anticavity"],"questions":["Questions? 1-800-285-9139"],"set_id":"2c1c5563-0b7e-4c7c-b49f-3d72e078cd28","spl_product_data_elements":["Crest Pro-Health Advanced w/Extra Whitening Sodium Fluoride WATER GLYCERIN HYDROGEN PEROXIDE POLOXAMER 407 POLYSORBATE 80 SACCHARIN SODIUM SUCRALOSE PHOSPHORIC ACID SODIUM PHOSPHATE, DIBASIC, ANHYDROUS SODIUM FLUORIDE FLUORIDE ION Clear"],"spl_unclassified_section":["Drug Facts","DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"version":"11","warnings":["Warnings Keep out of reach of children. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}